Cell Line Identity Typing
Identifying Cell Lines With A Common Ancestor
Over several decades, a number of cell lines have contaminated other cell cultures. The best known example is HeLa which has appeared under many other names. It is possible to identify samples derived from the same individual on the basis of their polymorphic marker genotypes ("DNA fingerprint"). The genotype information for all the cell lines and primary tumour DNAs analysed using the Affymetrix SNP arrays were compared by pair-wise analysis. A plot of the pair-wise comparisons against percentage identity is shown. All comparisons which have an identity greater than 70% are included in the table shown below. These pairs of lines are highly likely to have been derived from the same individual and therefore most are probably derivatives of each other. |
Identity | Line 1 | Line 2 |
| 99.3 | 1301 | CEMC1 |
| 99.4 | 1301 | CEMC2 |
| 96.2 | 1156-Q-E | 833-KE |
| 92.4 | 1321N1 | U-118-MG |
| 99.1 | 41M-CISR | A2780 |
| 96.2 | 833-KE | 1156-Q-E |
| 99.1 | A2780 | 41M-CISR |
| 98.9 | A549 | A549SF |
| 98.9 | A549SF | A549 |
| 91.2 | AKI | MR1-3 |
| 91.2 | AKI | MR10-1 |
| 91.4 | AKI | EKVX |
| 91.8 | AKI | GLC-82 |
| 92.7 | AKI | J-111 |
| 92.8 | AKI | Hep2 |
| 93.0 | AKI | KB |
| 93.9 | AKI | D98-AH2-CloneB |
| 95.6 | AKI | HeLaSF |
| 98.8 | AU565 | SK-BR-3 |
| 100.0 | AZ-521 | HUTU-80 |
| 92.3 | B2-17 | KNS-89 |
| 93.6 | B2-17 | TK-1 |
| 96.2 | B2-17 | U-251-MG |
| 96.9 | B2-17 | U-373-MG |
| 73.1 | BB65-RCC | LB996-RCC |
| 78.4 | BE | MDA-MB-231 |
| 98.1 | BE-13 | PEER |
| 98.1 | BE2-C | LAN-1 |
| 96.8 | BeWo | JEG-3 |
| 99.2 | C32 | C32TG |
| 99.2 | C32TG | C32 |
| 99.8 | Ca9-22 | KOSC-3 |
| 98.8 | CCRF-SB | CTV-1 |
| 99.3 | CEMC1 | 1301 |
| 99.8 | CEMC1 | CEMC2 |
| 99.4 | CEMC2 | 1301 |
| 99.8 | CEMC2 | CEMC1 |
| 99.0 | CGTH-W-1 | SW579 |
| 99.9 | CHI52 | PA-1 |
| 99.9 | CHI52 | LK1 |
| 95.7 | CHL-1 | COLO-699N |
| 98.6 | CHL-1 | HMCB |
| 96.1 | COLO-201 | COLO-206F |
| 97.6 | COLO-201 | COLO-205 |
| 96.6 | COLO-205 | COLO-206F |
| 97.6 | COLO-205 | COLO-201 |
| 96.1 | COLO-206F | COLO-201 |
| 96.6 | COLO-206F | COLO-205 |
| 95.9 | COLO-677 | COLO-775 |
| 99.9 | COLO-684 | COLO-704 |
| 94.7 | COLO-699N | HMCB |
| 95.7 | COLO-699N | CHL-1 |
| 99.9 | COLO-704 | COLO-684 |
| 95.9 | COLO-775 | COLO-677 |
| 95.2 | COLO-829 | COLO-858 |
| 98.3 | COLO-829 | COLO-849 |
| 93.7 | COLO-829 | COLO-853 |
| 93.7 | COLO-829 | COLO-857 |
| 93.1 | COLO-849 | COLO-858 |
| 98.3 | COLO-849 | COLO-829 |
| 91.9 | COLO-849 | COLO-853 |
| 91.8 | COLO-849 | COLO-857 |
| 99.7 | COLO-853 | COLO-857 |
| 99.3 | COLO-853 | COLO-858 |
| 93.7 | COLO-853 | COLO-829 |
| 91.9 | COLO-853 | COLO-849 |
| 99.4 | COLO-857 | COLO-858 |
| 93.7 | COLO-857 | COLO-829 |
| 91.8 | COLO-857 | COLO-849 |
| 99.7 | COLO-857 | COLO-853 |
| 93.1 | COLO-858 | COLO-849 |
| 95.2 | COLO-858 | COLO-829 |
| 99.3 | COLO-858 | COLO-853 |
| 99.4 | COLO-858 | COLO-857 |
| 99.9 | COR-L47 | COR-L51 |
| 99.9 | COR-L51 | COR-L47 |
| 98.8 | CTV-1 | CCRF-SB |
| 87.0 | CX-1 | MAwi |
| 97.5 | CX-1 | WIDR |
| 98.6 | CX-1 | HT-29 |
| 99.3 | D1-1 | Jurkat-clone-E6-1 |
| 99.7 | D1-1 | JM |
| 99.7 | D1-1 | J-RT3-T3-5 |
| 99.7 | D1-1 | J45-01 |
| 99.8 | D1-1 | H33HJ-JA1 |
| 88.8 | D98-AH2-CloneB | EKVX |
| 89.2 | D98-AH2-CloneB | GLC-82 |
| 90.1 | D98-AH2-CloneB | MR1-3 |
| 90.3 | D98-AH2-CloneB | MR10-1 |
| 90.9 | D98-AH2-CloneB | KB |
| 92.1 | D98-AH2-CloneB | Hep2 |
| 92.7 | D98-AH2-CloneB | J-111 |
| 93.4 | D98-AH2-CloneB | HeLaSF |
| 93.9 | D98-AH2-CloneB | AKI |
| 98.8 | DLD-1 | HCT-8 |
| 99.4 | DLD-1 | LUDLU-1 |
| 99.5 | DLD-1 | HRT-18 |
| 98.9 | EB1 | EB-2 |
| 99.8 | EB1 | EBC-1 |
| 98.9 | EB-2 | EB1 |
| 99.1 | EB-2 | EBC-1 |
| 99.1 | EBC-1 | EB-2 |
| 99.8 | EBC-1 | EB1 |
| 96.8 | EJ-1 | T24 |
| 88.8 | EKVX | D98-AH2-CloneB |
| 89.8 | EKVX | J-111 |
| 91.1 | EKVX | MR1-3 |
| 91.4 | EKVX | AKI |
| 91.5 | EKVX | MR10-1 |
| 92.7 | EKVX | HeLaSF |
| 94.7 | EKVX | Hep2 |
| 95.2 | EKVX | KB |
| 99.2 | EKVX | GLC-82 |
| 95.6 | FTC133 | FTC-238 |
| 95.6 | FTC-238 | FTC133 |
| 99.3 | GA-10-Clone-20 | ZR-75-1 |
| 99.9 | GA-10-Clone-20 | YMB-1 |
| 96.0 | GI-LI-N | IMR-32 |
| 97.6 | GI-LI-N | IMR-5 |
| 89.2 | GLC-82 | D98-AH2-CloneB |
| 89.8 | GLC-82 | J-111 |
| 91.5 | GLC-82 | MR1-3 |
| 91.8 | GLC-82 | AKI |
| 91.9 | GLC-82 | MR10-1 |
| 93.6 | GLC-82 | HeLaSF |
| 95.7 | GLC-82 | Hep2 |
| 95.9 | GLC-82 | KB |
| 99.2 | GLC-82 | EKVX |
| 100.0 | GOS-3 | KINGS-1 |
| 96.4 | GR-M | PSN1 |
| 99.3 | H33HJ-JA1 | Jurkat-clone-E6-1 |
| 99.8 | H33HJ-JA1 | J45-01 |
| 99.8 | H33HJ-JA1 | JM |
| 99.8 | H33HJ-JA1 | D1-1 |
| 99.8 | H33HJ-JA1 | J-RT3-T3-5 |
| 97.8 | H69 | NCI-H592 |
| 98.2 | H69 | NCI-H249 |
| 100.0 | H69 | NCI-H69 |
| 94.2 | HCT-15 | HT-115 |
| 98.8 | HCT-8 | DLD-1 |
| 98.9 | HCT-8 | HRT-18 |
| 99.2 | HCT-8 | LUDLU-1 |
| 93.6 | Hec1 | HEC-1-A |
| 93.6 | HEC-1-A | Hec1 |
| 98.7 | HEL | HEL-92-1-7 |
| 98.7 | HEL-92-1-7 | HEL |
| 91.9 | HeLaSF | MR10-1 |
| 92.2 | HeLaSF | MR1-3 |
| 92.7 | HeLaSF | EKVX |
| 93.4 | HeLaSF | D98-AH2-CloneB |
| 93.6 | HeLaSF | GLC-82 |
| 95.1 | HeLaSF | J-111 |
| 95.6 | HeLaSF | AKI |
| 95.8 | HeLaSF | Hep2 |
| 96.7 | HeLaSF | KB |
| 90.7 | Hep2 | MR1-3 |
| 90.9 | Hep2 | MR10-1 |
| 92.1 | Hep2 | D98-AH2-CloneB |
| 92.6 | Hep2 | J-111 |
| 92.8 | Hep2 | AKI |
| 94.7 | Hep2 | EKVX |
| 95.7 | Hep2 | GLC-82 |
| 95.8 | Hep2 | HeLaSF |
| 96.5 | Hep2 | KB |
| 96.9 | HL-60MX2 | P39-TSU |
| 94.7 | HMCB | COLO-699N |
| 98.6 | HMCB | CHL-1 |
| 95.0 | HOS | HTK |
| 98.9 | HRT-18 | HCT-8 |
| 99.5 | HRT-18 | DLD-1 |
| 99.6 | HRT-18 | LUDLU-1 |
| 94.2 | HT-115 | HCT-15 |
| 89.6 | HT-29 | MAwi |
| 98.6 | HT-29 | CX-1 |
| 98.7 | HT-29 | WIDR |
| 95.0 | HTK | HOS |
| 100.0 | HUTU-80 | AZ-521 |
| 100.0 | IGROV-1 | OVI-P |
| 95.6 | IMR-32 | IMR-5 |
| 96.0 | IMR-32 | GI-LI-N |
| 95.6 | IMR-5 | IMR-32 |
| 97.6 | IMR-5 | GI-LI-N |
| 89.8 | J-111 | GLC-82 |
| 89.8 | J-111 | EKVX |
| 91.5 | J-111 | MR1-3 |
| 91.6 | J-111 | MR10-1 |
| 92.6 | J-111 | Hep2 |
| 92.7 | J-111 | D98-AH2-CloneB |
| 92.7 | J-111 | AKI |
| 94.1 | J-111 | KB |
| 95.1 | J-111 | HeLaSF |
| 99.4 | J45-01 | Jurkat-clone-E6-1 |
| 99.7 | J45-01 | D1-1 |
| 99.8 | J45-01 | H33HJ-JA1 |
| 99.8 | J45-01 | JM |
| 99.9 | J45-01 | J-RT3-T3-5 |
| 96.8 | JEG-3 | BeWo |
| 99.3 | JM | Jurkat-clone-E6-1 |
| 99.7 | JM | D1-1 |
| 99.8 | JM | H33HJ-JA1 |
| 99.8 | JM | J-RT3-T3-5 |
| 99.8 | JM | J45-01 |
| 99.4 | J-RT3-T3-5 | Jurkat-clone-E6-1 |
| 99.7 | J-RT3-T3-5 | D1-1 |
| 99.8 | J-RT3-T3-5 | JM |
| 99.8 | J-RT3-T3-5 | H33HJ-JA1 |
| 99.9 | J-RT3-T3-5 | J45-01 |
| 99.3 | Jurkat-clone-E6-1 | H33HJ-JA1 |
| 99.3 | Jurkat-clone-E6-1 | D1-1 |
| 99.3 | Jurkat-clone-E6-1 | JM |
| 99.4 | Jurkat-clone-E6-1 | J45-01 |
| 99.4 | Jurkat-clone-E6-1 | J-RT3-T3-5 |
| 90.9 | KB | D98-AH2-CloneB |
| 91.2 | KB | MR10-1 |
| 91.2 | KB | MR1-3 |
| 93.0 | KB | AKI |
| 94.1 | KB | J-111 |
| 95.2 | KB | EKVX |
| 95.9 | KB | GLC-82 |
| 96.5 | KB | Hep2 |
| 96.7 | KB | HeLaSF |
| 100.0 | KINGS-1 | GOS-3 |
| 92.3 | KNS-89 | B2-17 |
| 95.6 | KNS-89 | U-373-MG |
| 97.6 | KNS-89 | TK-1 |
| 97.7 | KNS-89 | U-251-MG |
| 99.8 | KOSC-3 | Ca9-22 |
| 97.7 | KP4-1 | KP4-2 |
| 99.5 | KP4-1 | KP4-3 |
| 97.5 | KP4-2 | KP4-3 |
| 97.7 | KP4-2 | KP4-1 |
| 97.5 | KP4-3 | KP4-2 |
| 99.5 | KP4-3 | KP4-1 |
| 97.3 | KPL-1 | MCF7 |
| 98.1 | LAN-1 | BE2-C |
| 100.0 | LAN-5 | SH-SY5Y |
| 73.1 | LB996-RCC | BB65-RCC |
| 99.9 | LK1 | PA-1 |
| 99.9 | LK1 | CHI52 |
| 93.5 | LS-174T | SW839 |
| 99.6 | LS-174T | MT-3 |
| 99.7 | LS-174T | LSHM7 |
| 99.9 | LS-174T | LS-180 |
| 93.1 | LS-180 | SW839 |
| 99.5 | LS-180 | MT-3 |
| 99.8 | LS-180 | LSHM7 |
| 99.9 | LS-180 | LS-174T |
| 93.0 | LSHM7 | SW839 |
| 99.4 | LSHM7 | MT-3 |
| 99.7 | LSHM7 | LS-174T |
| 99.8 | LSHM7 | LS-180 |
| 98.5 | LU-65 | LU-65A |
| 98.5 | LU-65A | LU-65 |
| 99.2 | LUDLU-1 | HCT-8 |
| 99.4 | LUDLU-1 | DLD-1 |
| 99.6 | LUDLU-1 | HRT-18 |
| 99.6 | Marcus | SK-MG-1 |
| 99.8 | Marcus | RERF-LC-OK |
| 87.0 | MAwi | CX-1 |
| 89.4 | MAwi | WIDR |
| 89.6 | MAwi | HT-29 |
| 97.3 | MCF7 | KPL-1 |
| 94.7 | MC-SV-HUCT-2 | SV-HUC-1 |
| 70.2 | MDAH2774 | OC-315 |
| 70.3 | MDAH2774 | OC-314 |
| 70.3 | MDAH2774 | OC-316 |
| 74.9 | MDAH2774 | SW480 |
| 80.1 | MDAH2774 | SW527 |
| 81.8 | MDAH2774 | SW620 |
| 78.4 | MDA-MB-231 | BE |
| 98.5 | MKN28 | MKN74 |
| 98.5 | MKN74 | MKN28 |
| 90.3 | MR10-1 | D98-AH2-CloneB |
| 90.9 | MR10-1 | Hep2 |
| 91.2 | MR10-1 | AKI |
| 91.2 | MR10-1 | KB |
| 91.5 | MR10-1 | EKVX |
| 91.6 | MR10-1 | J-111 |
| 91.9 | MR10-1 | GLC-82 |
| 91.9 | MR10-1 | HeLaSF |
| 99.7 | MR10-1 | MR1-3 |
| 90.1 | MR1-3 | D98-AH2-CloneB |
| 90.7 | MR1-3 | Hep2 |
| 91.1 | MR1-3 | EKVX |
| 91.2 | MR1-3 | AKI |
| 91.2 | MR1-3 | KB |
| 91.5 | MR1-3 | GLC-82 |
| 91.5 | MR1-3 | J-111 |
| 92.2 | MR1-3 | HeLaSF |
| 99.7 | MR1-3 | MR10-1 |
| 93.5 | MT-3 | SW839 |
| 99.4 | MT-3 | LSHM7 |
| 99.5 | MT-3 | LS-180 |
| 99.6 | MT-3 | LS-174T |
| 97.5 | MUTZ-1 | NAMALWA |
| 97.5 | NAMALWA | MUTZ-1 |
| 98.7 | NCI-ADR-RES | OVCAR8 |
| 97.5 | NCI-H1264 | NCI-H157 |
| 97.5 | NCI-H157 | NCI-H1264 |
| 93.7 | NCI-H1770 | NCI-H2106 |
| 89.3 | NCI-H1993 | NCI-H2073 |
| 95.5 | NCI-H1994 | NCI-H2029 |
| 95.5 | NCI-H2029 | NCI-H1994 |
| 99.1 | NCI-H2059 | NCI-H2141 |
| 89.3 | NCI-H2073 | NCI-H1993 |
| 93.7 | NCI-H2106 | NCI-H1770 |
| 99.1 | NCI-H2141 | NCI-H2059 |
| 97.9 | NCI-H2196 | NCI-H2198 |
| 97.9 | NCI-H2198 | NCI-H2196 |
| 98.1 | NCI-H249 | NCI-H69 |
| 98.2 | NCI-H249 | H69 |
| 99.4 | NCI-H249 | NCI-H592 |
| 98.9 | NCI-H322 | NCI-H322M |
| 98.9 | NCI-H322M | NCI-H322 |
| 94.6 | NCI-H417 | NCI-H60 |
| 97.8 | NCI-H592 | NCI-H69 |
| 97.8 | NCI-H592 | H69 |
| 99.4 | NCI-H592 | NCI-H249 |
| 94.6 | NCI-H60 | NCI-H417 |
| 97.8 | NCI-H69 | NCI-H592 |
| 98.1 | NCI-H69 | NCI-H249 |
| 100.0 | NCI-H69 | H69 |
| 99.9 | NCI-H727 | NCI-H735 |
| 99.9 | NCI-H735 | NCI-H727 |
| 99.1 | NT2-D1 | NTERA-S-cl-D1 |
| 99.1 | NTERA-S-cl-D1 | NT2-D1 |
| 70.3 | OC-314 | MDAH2774 |
| 99.8 | OC-314 | OC-316 |
| 99.9 | OC-314 | OC-315 |
| 70.2 | OC-315 | MDAH2774 |
| 99.7 | OC-315 | OC-316 |
| 99.9 | OC-315 | OC-314 |
| 70.3 | OC-316 | MDAH2774 |
| 99.7 | OC-316 | OC-315 |
| 99.8 | OC-316 | OC-314 |
| 97.8 | OCUB-F | OCUB-M |
| 97.8 | OCUB-M | OCUB-F |
| 98.7 | OVCAR8 | NCI-ADR-RES |
| 100.0 | OVI-P | IGROV-1 |
| 96.9 | P39-TSU | HL-60MX2 |
| 99.9 | PA-1 | LK1 |
| 99.9 | PA-1 | CHI52 |
| 98.1 | PEER | BE-13 |
| 96.4 | PSN1 | GR-M |
| 99.1 | Ramos-2G6-4C10 | Ramos-RA-1 |
| 99.1 | Ramos-RA-1 | Ramos-2G6-4C10 |
| 97.5 | RD | T-174 |
| 97.6 | RD | TE-130-T |
| 97.8 | RD | TE-76-T |
| 99.2 | RERF-LC-OK | SK-MG-1 |
| 99.8 | RERF-LC-OK | Marcus |
| 99.4 | SH-4 | TE-159-T |
| 100.0 | SH-SY5Y | LAN-5 |
| 99.0 | Ska-3-68 | SK-OV-3 |
| 98.8 | SK-BR-3 | AU565 |
| 99.3 | SK-MEL-2 | SK-MEL-31 |
| 99.3 | SK-MEL-31 | SK-MEL-2 |
| 99.2 | SK-MG-1 | RERF-LC-OK |
| 99.6 | SK-MG-1 | Marcus |
| 99.0 | SK-OV-3 | Ska-3-68 |
| 99.5 | SNU-C2A | SNU-C2B |
| 99.5 | SNU-C2B | SNU-C2A |
| 95.3 | SR | SR-786 |
| 95.3 | SR-786 | SR |
| 94.7 | SV-HUC-1 | MC-SV-HUCT-2 |
| 74.9 | SW480 | MDAH2774 |
| 88.0 | SW480 | SW620 |
| 89.3 | SW480 | SW527 |
| 80.1 | SW527 | MDAH2774 |
| 89.3 | SW527 | SW480 |
| 94.2 | SW527 | SW620 |
| 99.0 | SW579 | CGTH-W-1 |
| 81.8 | SW620 | MDAH2774 |
| 88.0 | SW620 | SW480 |
| 94.2 | SW620 | SW527 |
| 93.0 | SW839 | LSHM7 |
| 93.1 | SW839 | LS-180 |
| 93.5 | SW839 | LS-174T |
| 93.5 | SW839 | MT-3 |
| 97.5 | T-174 | RD |
| 99.3 | T-174 | TE-130-T |
| 99.9 | T-174 | TE-76-T |
| 96.8 | T24 | EJ-1 |
| 97.6 | TE-130-T | RD |
| 99.3 | TE-130-T | T-174 |
| 99.4 | TE-130-T | TE-76-T |
| 99.4 | TE-159-T | SH-4 |
| 97.8 | TE-76-T | RD |
| 99.4 | TE-76-T | TE-130-T |
| 99.9 | TE-76-T | T-174 |
| 93.2 | TGW | TNB-1 |
| 93.6 | TK-1 | B2-17 |
| 96.9 | TK-1 | U-373-MG |
| 97.6 | TK-1 | KNS-89 |
| 97.6 | TK-1 | U-251-MG |
| 93.2 | TNB-1 | TGW |
| 99.0 | TUR | U-937 |
| 92.4 | U-118-MG | 1321N1 |
| 96.2 | U-251-MG | B2-17 |
| 99.5 | U-251-MG | U-373-MG |
| 97.7 | U-251-MG | KNS-89 |
| 97.6 | U-251-MG | TK-1 |
| 95.6 | U-373-MG | KNS-89 |
| 96.9 | U-373-MG | B2-17 |
| 96.9 | U-373-MG | TK-1 |
| 99.5 | U-373-MG | U-251-MG |
| 99.0 | U-937 | TUR |
| 89.4 | WIDR | MAwi |
| 97.5 | WIDR | CX-1 |
| 98.7 | WIDR | HT-29 |
| 99.3 | YMB-1 | ZR-75-1 |
| 99.9 | YMB-1 | GA-10-Clone-20 |
| 99.3 | ZR-75-1 | YMB-1 |
| 99.3 | ZR-75-1 | GA-10-Clone-20 |
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