17.05.12 Untangling the development of breast cancer
- BBC World Service - Science in action 17.05.2012
- Reuters - Study unpicks gene changes behind breast cancer 17.05.2012
- Chicago Tribune - Study unpicks gene changes behind breast cancer 17.05.2012
- Fox News - Study unpicks gene changes behind breast cancer 17.05.2012
Researchers sequenced the genomes of 21 breast cancers and analysed the mutations that emerged during the tumours' development. The results of each paper are explored in more detail in the accompanying press releases on mutation processes and on evolution in breast cancers. [Press Release]
16.05.12 Understanding breast cancer
- MSN News - Genetic breast cancer 'map' drawn 17.05.2012
- LA Times - Breast cancer study reveals 'substantial genetic diversity' 16.05.2012
Researchers describe nine new genes that drive the development of breast cancer. This takes the tally of all genes associated with breast cancer development to 40. [Press Release]
29.04.12 Gene against pancreatic cancer discovered
- BBC News - 'Brake gene' turned off in pancreatic cancer 30.04.2012
- Sydney Morning Herald - New hope in pancreas cancer treatment 29.04.2012
- Huffington Post - New Hope For Pancreatic Cancer Sufferers 30.04.2012
Researchers identified a potential new therapeutic target for pancreatic cancer. The team found that when a gene involved in protein degradation is switched-off through chemical tags on the DNA's surface, pancreatic cancer cells are protected from the bodies' natural cell death processes, become more aggressive, and can rapidly spread. [Press Release]
19.04.12 Key genes that switch off with ageing identified
- ITV News - The secret to how we age 20.04.2012
- The Independent - Breakthrough announced in ageing genes study 20.04.2012
- Daily Mail - Who wants to live forever? Genetic breakthrough could pave way for drugs that slow - or halt - the ageing process 21.04.2012
Scientists identified a group of 'ageing' genes that are switched on and off by natural mechanisms called epigenetic factors, influencing the rate of healthy ageing and potential longevity. [Press Release]
28.03.12 The path to personalised cancer treatment
- BBC News Online - Cancer: 'Book of knowledge' published 29.03.2012
- Nature News - Cancer screen yields drug clues 28.03.2012
- The Scientist - Collecting Cancer Data 29.03.2012
In the largest study of its kind, researchers have profiled genetic changes in cancer with drug sensitivity in order to develop a personalised approach to cancer treatments. [Press Release]
25.03.12 Genetics of flu susceptibility
- Time Magazine - Why Flu Hits Some Harder than Others 26.03.2012
- New Scientist - Mutant protein may allow flu to kill 26.03.2012
- Independent - Gene that fights flu identified 26.03.2012
- BBC News Online - Gene flaw linked to serious flu risk 25.03.2012
- Reuters - Scientists find gene that can make flu a killer 25.03.2012
- Daily Mail - Genetic flaw that turns flu into a killer discovered 25.03.2012
- Huffington post - Flu-Fighting Ability Could Lie In Person's Genes 26.03.2012
A genetic finding could help explain why influenza becomes a life-threating disease to some people while it has only mild effects in others. New research led by the Wellcome Trust Sanger Institute has identified for the first time a human gene that influences how we respond to influenza infection. [Press Release]
22.03.12 Subtle differences can lead to major changes in parasites
- Science Daily - Subtle Differences Can Lead to Major Changes in Parasites 23.03.2012
Researchers have found the subtle genetic differences that make one parasite far more virulent than its close relative. [Press Release]
11.03.12 Tracing the UK's No1 sexually transmitted infection
- Daily Mail - Chlamydia is a 'cunning' STI that easily evolves into new strains, discover scientists 11.03.2012
- Yahoo! News - How Chlamydia Evolves into New Strains 12.03.2012
Researchers found that Chlamydia has evolved more actively than was previously thought. Using whole genome sequencing the researchers show that the exchange of DNA between different strains of Chlamydia to form new strains is much more common than expected. [Press Release]
07.03.12 What have we got in common with a Gorilla?
- CNN - First gorilla genome map offers clues to human evolution 13.03.2012
- Scientific American - Gorilla Joins the Genome Club 07.03.2012
- Aljazeera - Gorillas are a lot like us 08.03.2012
- Los Angeles Times - Gorilla DNA offers clues about humans too 07.03.2012
- USA Today - Genome study finds similarities between DNA of gorillas, humans 08.03.2012
- Sydney Morning Herald - Scientists unlock genetic code for gorillas - and show the human link 09.03.2012
- The Guardian - Gorilla genome analysis reveals new human links 07.03.2012
- BBC News - Gorilla genome could hold key to the human condition 07.03.2012
- Reuters - Gorilla genome sheds new light on human evolution 07.03.2012
- Le Monde - Génétique : le gorille et l'homme ont plus en commun que prévu 07.03.2012
- National Geographic - Gorillas More Related to People Than Thought, Genome Says 07.03.2012
Researchers completed the genome sequence for the gorilla - the last genus of the living great apes to have its genome decoded. While confirming that our closest relative is the chimpanzee, the team show that much of the human genome more closely resembles the gorilla than it does the chimpanzee genome. [Press Release]
26.02.12 Elusive platelet count and limb development gene discovered
- Genome Web - Exome Sequencing Study of Rare Syndrome Points to Compound Inheritance Involving Regulatory Variants 27.02.2012
Researchers identified an elusive gene responsible for Thrombocytopenia with Absent Radii (TAR), a rare inherited blood and skeletal disorder. As a result, this research is now being transformed into a medical test that allows prenatal diagnosis and genetic counselling in affected families. [Press Release]
16.02.12 When is a gene not a gene?
- Washington Post - Genome news flash: We're all a little bit broken 16.02.2012
- Science - The Case of the Missing Genes 16.02.2012
- Discover Magazine - Extraordinary mutations require extraordinary evidence 19.02.2012
- Reuters - Study finds one percent of human genes switched off 16.02.2012
A high-quality reference catalogue of the genetic changes that result in the deactivation of human genes has been developed by a team of researchers. This catalogue of loss-of-function (LoF) variants is needed to find new disease-causing mutations and will help us to better understand the normal function of human genes. [Press Release]
16.02.12 Preventing the devil's downfall
- BBC News - Tasmanian devils' killer disease genome mapped 17.02.2012
- Daily Mail - Last-ditch DNA battle to save Tasmanian devil from extinction at hands of contagious cancer spread by biting 16.02.2012
- Nature News - Field narrows in hunt for devil tumour genes 16.02.2012
- New Scientist - 'Immortal' Tasmanian devil brings vaccine hope 17.02.2012
- Scientific American - Contagious Cancer: Genome Study Reveals How Tasmanian Devil Cancer Has Spread 17.02.2012
- ABC News - Devil tumour origin discovered 17.02.2012
- Reuters - Tasmanian devil genome mapping may help humans too 17.02.2012
Researchers sequenced the genome of a contagious cancer that is threatening the Tasmanian devil, the world's largest carnivorous marsupial, with extinction. Cataloguing the mutations present in the cancer has led to clues about where the cancer came from and how it became contagious. [Press Release]
02.02.12 Paths to Cardiovascular Diseases and Type 2 Diabetes
- Science Daily - Genetic Regulation of Metabolomic Biomarkers: Paths to Cardiovascular Diseases and Type 2 Diabetes 29.01.2012
Researchers found 31 regions on the genome that associate with biological indicators of common diseases such as cardiovascular disease and type II diabetes. These results may provide valuable insights into the biological processes of common and often fatal diseases. [Press Release]
31.01.12 What are your views on what happens to your genomic information?
- Channel 4 News - Do you want to know what diseases lie in store? 31.01.2012
- Channel 4 News - What your genes could mean 31.01.2012
- Pharma Times - Sanger Institute survey tests waters on genomic data use 31.01.2011
An ethics team from the Wellcome Trust Sanger Institute launch an online survey to capture the views of as many people as possible: they hope it will be the largest collection of opinions gathered to date. [Press Release]
25.01.12 Genetic screens bring new hope for tackling sleeping sickness
- New Scientist - Sleeping sickness tests may identify better therapies 25.01.2012
- Voice of America - Scientists Develop Tool to Unmask Sleeping Sickness Resistance 26.01.2012
Research has exploited a revolutionary genetic technique to discover how human African Trypanosomiasis (HAT) drugs target the parasite which causes the disease. [Press Release]

