The Sanger Institute in the Media - 2009

Since the Sanger Institute's inception, we have been involved in groundbreaking discoveries and projects which have received significant attention from the media worldwide. These pages provide an archive of selected news coverage around some of the Sanger Institute's recent research findings.

[Wellcome Library, London]

23.12.09 Broken genomes behind breast cancers

Researchers led by the Wellcome Trust Sanger Institute publish the first detailed search of breast cancer genomes to uncover genomic rearrangements. They characterise the ways in which the human genome is broken and put back together in 24 cases of breast cancer. [press release]

16.12.09 Lung cancer and melanoma laid bare

Research teams led by the Wellcome Trust Sanger Institute announce the first comprehensive analyses of cancer genomes. The landmark studies, of a malignant melanoma and a lung cancer, reveal for the first time essentially all the mutations in the genomes of two cancers. [press release]

06.12.09 Genetic studies reveal new causes of severe obesity in childhood

Scientists, including Sanger Institute researchers discover that the loss of a key segment of DNA can lead to severe childhood obesity. It is the first study to show that this kind of genetic alteration can cause obesity. [press release]

02.11.09 First draft of pig genome complete

A global collaborative produces the first draft of the genome of the domesticated pig. The sequencing effort, most of which was performed at the Sanger Intitute opens new doors to understanding human disease. [press release]

11.10.09 Blood counts are clues to human disease

GenomeWeb reports the identification of 22 new regions associated with blood cell traits. The study begins to uncover how basic ciological processes interact to influence health and disease. [press release]

27.08.09 We are all mutants: measurement of human mutation rate by direct sequencing

An international team led by the Sanger Institute successfully measures the general rate of mutation at individual DNA letters in humans. The team sequenced the sections from the Y chromosomes of two distant male-line relatives separated by 13 generations and found just four differences in their genetic code. [press release]

15.07.09 Genome sequencers crack Schistosoma mansoni genome

A Sanger Institute led team decodes the genome of S. mansoni, the parasite which every year causes 200 million cases of schistosomiasis and 280,000 deaths in sub-Saharan Africa alone. Journalists report how the results have the potential to uncover new drug targets. [press release]

14.06.09 Knockout results for mouse genetics

In Sciences reports the results of a collaboration including the Sanger Institute. The team have developed embryonic stem cells that are ideal for high-throughput genetic manipulation and will provide a foundation for two knockout programmes. [press release]

31.05.09 First testicular cancer risk genes found

Journalists report research carried out in collaboration between the Institute of Cancer Research and the Sanger Institute. The team found three genetic variants that, in combination, can increase the risk of testicular cancer fourfold. [press release]

24.05.09 New tools to researchers in fight against malaria

Because of higher levels of genetic diversity in Africa, genome-wide association studies for African populations can be difficult to complete. The Scientist reports on research that will allow more studies of genetic variants that lead to susceptibility to malaria in African populations. [press release]

19.04.09 X linked learning disabilities

The Times and the Guardian both report research led by the Sanger Institute that uncovers nine genes on the X chromosome that are implicated in learning difficulties in males. [press release]

12.04.09 MicroRNA gene that causes hearing loss

These reports cover new findings in parallel studies in human and mouse. A team of researchers from the Sanger Institute and a team from the Hospital RamÃn y Cajal, Madrid, Spain, have come to the same conclusion: that a new kind of gene - a microRNA - is associated with progressive hearing loss. [press release]

27.03.09 Strangles and horse disease

Horse and Hound reports the sequencing of the Streptococcus equi pathogen, which devastates the horse world, causing strangles. [press release]

23.02.09 Warfarin dosing

These two reports detail how research led by the Sanger Institute could impact methods around Warfarin dosing. They detail how the ideal dose of the blood-thinning drug, Warfarin, is in part genetically determined. The research is a part of a move towards personalized medicine. [press release]

05.02.09 Superfluous genes?

Genome Web Daily News reports the remarkable finding that one in 200 genes in the human body might be superfluous. The article is based on research from the Sanger Institute that finds single letter changes in the human genome that inactivate genes without any visible effect. [press release]

18.01.09 Heart disease mutation that strikes India

Global media report research carried out in collaboration between the Sanger Institute and the Centre for Cellular and Molecular Biology in Hyderabad, India. The team discovered a mutation, a deletion of 25 letters of genetic code from the heart protein gene MYBPC3, which is virtually restricted to people from the Indian subcontinent. It was discovered some years ago, but its significance has now been revealed. [press release]

The Sanger Institute in the Media

Contact the Press Office

Don Powell Media and Public Relations Manager
Wellcome Trust Sanger Institute, Hinxton, Cambs, CB10 1SA, UK

Tel +44 (0)1223 496 928
Mobile +44 (0)7753 775 397
Fax +44 (0)1223 494 919
Email press.office@sanger.ac.uk

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