The Sanger Institute has been funded to sequence selected isolates from the remaining Yersinia enterocolitica biotypes that have distinct biochemical and virulence properties, using a combination of conventional capillary sequencing and 454 technology in collaboration with Brendan Wren and Sarah Howard of the Wren Department of Infectious & Tropical Diseases, London School of Hygiene & Tropical Medicine, Alan McNally of the School of Biomedical and Natural Sciences, Nottingham Trent University and Michael Prentice of the Departments of Microbiology and Pathology, University College Cork. PD Dr. Thilo M. Fuchs of ZIEL, Department of Microbiology, TU München and Dr Muriel Dufour of ESR NCBID - Wallaceville, New Zealand have joined us in collaborating on our goal to sequence a global Yersinia entericolitica biotype collection.
Isolates will be selected on the basis of biotype differences and their significance as pathogens. Included will be human clinical, livestock-specific, human low-pathogenic and human high-pathogenic isolates.
