Trypanosoma brucei Genome Project

Data Release Statement

This sequencing centre plans on publishing the completed and annotated sequences in a peer-reviewed journal as soon as possible. Permission of the principal investigator should be obtained before publishing analyses of the sequence/open reading frames/genes on a chromosome or genome scale.

T. brucei possesses a two-unit genome, a nuclear genome and a mitochondrial (kinetoplast) genome with a total estimated size of 35Mb/haploid genome. The nuclear genome is split into three classes of chromosomes according to their size on pulsed-field gel electrophoresis, 11 pairs of megabase chromosomes (0.9-5.7 Mb), intermediate (300-900 kb) and minichromosomes (50-100 kb) (click here for further information as well as a picture and map of pulse field separated chromosomes).

The T. brucei project at the Sanger Institute encompasses sequencing the parasite's genome in conjunction with development of a database resource (GeneDB) for the integration of sequence, annotation and functional data generated by the research community. These project pages are designed to provide background information on T. brucei and the sequencing projects as well as facilitating access to the sequence, annotation and analysis.

Information