Streptococcus suis

The Sanger Institute has completed the sequencing of and recently published the genome of three S. suis strains (P1/7, BM407 and SC84) in collaboration with Prof. Duncan Maskell of the Centre for Veterinary Science, Dept. of Clinical Veterinary Medicine, The University of Cambridge, Prof. Mike Kehoe of the School of Cell and Molecular Biosciences, University of Newcastle, Dr. Jamie Leigh and Dr. Phil Ward of the Institute for Animal Health, Compton, Prof. Christopher Dowson and Dr. Adrian Whatmore, of the Department of Biological Sciences, University of Warwick, and Dr. Neil Chanter of the Centre for Preventative Medicine, Animal Health Trust, Dr. Constance Schultsz of the Oxford University Clinical Research Unit/Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam, Prof. Duncan Maskell of the Centre for Veterinary Science, Dept. of Clinical Veterinary Medicine, The University of Cambridge, Dr. Marcelo Gottschalk of GREMIP, University of Montreal, Canada, Dr. Josh Slater of the Royal Veterinary College, London, Dr. Hilde Smith of the Animal Sciences Group of Wageningen UR, Lelystad, Netherlands, Prof. Brian Spratt of the Department of Infectious Disease Epidemiology, Imperial College, London and Dr. Jianguo Xe and Dr. Changyun Ye of the State Key Laboratory for Infectious Disease Prevention and Control and National Institute for Communicable Disease Control and Prevention, China CDC, Beijing, China.

S. suis is a pathogen of both pigs and humans, causing meningitis where pigs and humans are in close contact, especially in tropical regions.

		Streptococcus suis Data     The complete P1/7 chromosome sequence and annotation in Artemis format.     The complete BM407 chromosome sequence and annotation in Artemis format.     The BM407 plasmid sequence and annotation in Artemis format.     The complete SC84 chromosome sequence and annotation in Artemis format.     A BLAST server allowing searching of the chromosome sequences and predicted CDSs.     FTP access to the sequences and CDS databases.

The sequences and annotations of the Streptococcus suis P1/7, SC84 and BM407 genomes have been deposited in the EMBL database under accession numbers AM946016, FM252031, FM252032 and FM252033 respectively.

Reference:

"Rapid evolution of virulence and drug resistance in the emerging zoonotic pathogen Streptococcus suis" (2009) PLoS One 4(7):e6072.

Matthew T.G. Holden, Heidi Hauser, Mandy Sanders, Ngo Thi Hoa, Inna Cherevach, Ann Cronin, Ian Goodhead, Karen Mungall, Michael A. Quail, Claire Price, Ester Rabbinowitsch, Sarah Sharp, Nicholas J. Croucher, Tran Bich Chieu, Nguyen Thi Hoang Mai, To Song Diep, Nguyen Tran Chinh, Michael Kehoe, James A. Leigh, Philip N. Ward, Christopher G. Dowson, Adrian M. Whatmore, Neil Chanter, Pernille Iversen, Marcelo Gottschalk, Josh D. Slater, Hilde E. Smith, Brian G. Spratt, Jianguo Xu, Changyun Ye, Stephen Bentley, Barclay G. Barrell, Constance Schultsz, Duncan J. Maskell and Julian Parkhill

Available from this FTP site are data files from a single lane of a recent Illumina run on the S. suis P1/7 genome. These files are provided for the purpose of real-life data format explorations by both the short-sequence read format and new assembly format community. It is an example data set only, and should not be considered to be representative of every Illumina run. Please read the README file on the FTP site for more information.