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Retrieve BLAST result
Protozoan Genomes

The Sanger Institute protozoan sequencing effort is concentrated on pathogens and model organisms. Below is a list of projects funded, underway or completed; all data from these projects are immediately and freely available.

Data are accessible in a number of ways; for each organism there is a BLAST server, allowing you to search the sequences with your own query. Sequences can also be downloaded directly by FTP. In addition, for those organisms being sequenced using a cosmid approach, finished and annotated cosmids are submitted to EMBL and other public databases (these continue to be accessible by BLAST and FTP from here). Enquiries about sequencing or analysis should be directed to Matt Berriman.

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  Organism Size (Mb) Status Funding
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Babesia bigemina  
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  Whole Genome Shotgun 10 Mb Shotgun Complete Wellcome Trust

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Babesia bovis  
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  EST Sequencing 10,000 reads ~1600 reads NWO
WOTRO

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Bodo saltans  
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  Whole Genome Sequencing ~35 Mb Sequencing Wellcome Trust

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Crithidia sp.  
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  Whole Genome Shotgun ~35 Mb Sequencing Wellcome Trust

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Dictyostelium discoideum    Eichinger et al. Nature 435: 43-57 (2005)
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  chromosome 6 1.5 fragment Draft sequence European Commission
  chromosome 5 5.5 Draft sequence Medical Research Council

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Eimeria tenella  
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  partial genome shotgun ~ 60 draft assembly BBSRC

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Entamoeba dispar  
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  Genome Survey Sequencing 20,000 reads Shotgun complete BBSRC
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Entamoeba histolytica    Loftus et al. Nature 433: 865-8 (2005)
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  Whole Genome Shotgun 20 Mb Draft sequence Wellcome Trust
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Entamoeba invadens  
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  Genome Survey Sequencing 20,000 reads Shotgun complete BBSRC
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Entamoeba moshkovskii  
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  Genome Survey Sequencing 20,000 reads Shotgun complete BBSRC
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Entamoeba terrapinae  
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  Genome Survey Sequences 20,000 reads Shotgun complete BBSRC

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Leishmania braziliensis    Peacock et al. Nat. Genet. 39: 839-47 (2007)
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  Whole genome shotgun (5x) ~33.5 High quality draft sequence Wellcome Trust
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Leishmania infantum    Peacock et al. Nat. Genet. 39: 839-47 (2007)
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  Whole genome shotgun (5x) ~33.5 High quality draft sequence Wellcome Trust
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Leishmania major    Ivens et al. Science 309: 436-42 (2005)
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  Chromosomes 4-26,28,30-34,36 27.8 Finished (barring 2 gaps) Beowulf Genomics/Wellcome Trust
European Commission
Leishmania mexicana  
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  Whole genome shotgun (5x) ~33.5 sequencing Wellcome Trust

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Leptomonas seymouri   
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  4x coverage ~35 sequencing Wellcome Trust

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Neospora caninum  
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  whole genome shotgun ~55 Sequencing BBSRC

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Plasmodium projects (malaria)
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Plasmodium berghei
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  Whole Genome Shotgun 25 Mb 8 fold coverage Wellcome Trust
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Plasmodium chabaudi  
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  Whole Genome Shotgun 25 Mb 8 fold coverage Wellcome Trust
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Plasmodium falciparum
   Gardner et al. Nature 419: 498-511 (2002)
Hall et al. Nature 419: 527-531 (2002)
Bowman et al. Nature 400: 532-538 (1999)
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  • Clone 3D7
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      Chromosomes 1,3-9,13 23 Mb final stages of finishing Wellcome Trust
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  • Ghanaian clinical isolate
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      Whole Genome Shotgun 23 Mb 8 fold coverage Wellcome Trust
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  • IT strain
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      Whole Genome Shotgun 23 Mb Sequencing, 8 fold coverage European Union (FP6)
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    Plasmodium gallinaceum  
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      Whole Genome Shotgun 25 Mb 3 fold coverage Wellcome Trust
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    Plasmodium knowlesi    Pain et al. Nature 455: 799-803 (2008)
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      Whole Genome Shotgun 25 Mb High quality draft Wellcome Trust
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    Plasmodium ovale  
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      Whole Genome Shotgun 25 Mb Sequencing Wellcome Trust
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    Plasmodium reichenowi  
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       Partial Genome Shotgun 25-27Mb Sequencing Wellcome Trust
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    Plasmodium vivax  
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      IVD10 YAC sequence 156 kb Finished Wellcome Trust

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    Theileria annulata    Pain et al. Science 309: 131-133 (2005)
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      whole genome shotgun 10 Finished
    Beowulf Genomics
      EST Sequencing 10,000 reads Finished NWO
    WOTRO

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    Toxoplasma gondii  
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      Whole Genome BAC end sequencing 80Mb Sequencing Beowulf Genomics
      Chromosome I 3Mb Finished
    Khan et al. Genome Res. 16: 1119-25 (2006)
    Beowulf Genomics

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    Trypanosoma brucei    Berriman et al. Science 309: 416-22 (2005)
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      VSG expression site BACs - Finished
    Berriman et al. Mol Biochem Parasitol 122: 131-140 (2002)
    Beowulf Genomics
      chromosome I 1.1 Finished
    Hall et al. Nuc Acids Res 31: 4864-4873 (2003)
    Beowulf Genomics
      chromosomes IX, X, XI 13.1 In finishing Beowulf Genomics
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    Trypanosoma congolense  
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      Partial Genome Shotgun ~ 25Mb in assembly
    (at 5x coverage)
    Wellcome Trust
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    Trypanosoma brucei gambiense  
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      Partial Genome Shotgun ~ 25Mb Finishing
    (at 8x coverage)
    Wellcome Trust
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    Trypanosoma vivax  
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      Partial Genome Shotgun ~ 25Mb in assembly
    (at 5x coverage)
    Wellcome Trust


    Data Release Statement

    This sequencing centre plans on publishing the completed and annotated sequences in a peer-reviewed journal as soon as possible. Permission of the principal investigator should be obtained before publishing analyses of the sequence/open reading frames/genes on a chromosome or genome scale.

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    Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK  Tel:+44 (0)1223 834244

    Last Modified Tue Sep 8 12:49:33 2009

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