The Project
The Wellcome Trust Sanger Institute Pathogen Genomics group is undertaking partial shotgun sequencing of a number of different species of Plasmodium. This will serve as a useful comparative genomics resource to complement the almost complete Plasmodium falciparum genome. This work is being done in collaboration with Chris Newbold (Oxford) and Mike Turner (Glasgow).
The chimpanzee malaria parasite P. reichenowi is phylogenetically closest to the human parasite P. falciparum. Both parasites differ in vertebrate and invertebrate host specificity, but morphologically and at the gene/protein level, they are quite similar. P. reichenowi has an estimated genome size of 25-27Mb in 14 chromosomes
Library construction
Genomic libraries were constructed in the pUC18 vector from P. reichenowi Dennis strain total genomic DNA provided by Alan Thomas at the BPRC (Netherlands).
ALL SEQUENCE DATA IS CURRENTLY PRELIMINARY AND STILL CONTAINS A HIGH LEVEL OF HOST DNA
Searching the P. reichenowi genomic sequence online
You can also search against P. reichenowi genomic sequence using our online BLAST server.
Accessing the P. reichenowi Sequence data
Sequence data can be downloaded from the FTP site.
