M.microti

The Sanger Institute is sequencing the genome of Mycobacterium microti strain OV254 in collaboration with Dr. Stewart Cole at the Unit de Genetique Moleculaire Bacterienne, Institut Pasteur and Dr. Glyn Hewinson at the Veterinary Laboratories Agency, with funding from DEFRA.

M. microti causes tuberculosis in rodents and has previously been evaluated a live vaccine for humans.

Finishing of the genome will be carried out at the Institut Pasteur, and further information is available from their website

At present, there are 71,086 reads in the database, totalling 36.468 Mb and giving a theoretical coverage of 99.97% of the genome. The data is available for download by FTP and can be searched using our BLAST server.

Test assemblies of M. microti have now begun; a database containing the latest assembly is available in the same way.

At present there are 468 contigs > 1kb (316 contigs >2kb) with a tot al size of 4.258 Mb

Assembly warning

Please note that the assembly database consists of unedited automatic assemblies; it will contain errors and misassemblies, along with E. coli and vector contamination. The contig numbers are not stable, and will vary with each data release. The sequences in the shotgun database are single reads from ABI sequencers; they will contain errors, along with both E. coli and vector contamination.

Data Release Statement

This sequencing centre plans on publishing the completed and annotated sequences in a peer-reviewed journal as soon as possible. Permission of the principal investigator should be obtained before publishing analyses of the sequence/open reading frames/genes on a chromosome or genome scale.

Sequencing enquiries

Please address all sequencing enquiries to: parkhill@sanger.ac.uk

webmaster@sanger.ac.uk

Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK Tel:+44 (0)1223 834244

Last Modified Fri Apr 23 13:09:36 2004

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