The Sanger Institute has been funded by Beowulf Genomics to sequence the genome of M. marimum in collaboration with Dr. Lalita Ramakrishnan of the Department of Microbiology, University of Washington, Seattle, Dr. Stewart Cole of the Unit de Genetique Moleculaire Bacterienne, Institut Pasteur, Dr. John Davies of the Department of Microbiology, Monash University, Australia, Dr. Pamela Small of the Department of Microbiology, University of Tennessee, Knoxville, and Dr. Paul Johnson of the Department of Infections Diseases, Monash Medical Centre, Australia.
M. marinum is a close relative of M. tuberculosis that causes a tuberculosis-like disease in frogs, fish and other cold-blooded animals, and a peripheral granulomatous disease in humans. We sequenced strain ATCC BAA-535, isolated from a patient at Moffett Hospital at UCSF.
The sequence and analysis is described in Stinear et al (2008) Genome Research (online publication). The sequence and annotation have been submitted to the GenBank/EMBL databases with accession numbers CP000854 (chromosome) and CP000895 (plasmid).
The finished genome is also available for searching on our Blast Server, or for download from our FTP site.
The genome is 6,636,827 bp in length, with an average G+C content of 65.73 %
The shotgun data is still available: there are 138,601 reads totalling 59.714 Mb and giving a theoretical coverage of 99.99% of the genome.



