| Gene name: | Class: | Start/End: | Length: | Molecular weight: | |
|---|---|---|---|---|---|
| guaB3 | ML0388 | I.F.1 | 482274 / 483386 | 1113 bp / 370 aa | 38394 Da |
| Product: | |||||
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putative inosine-5'-monophosphate dehydrogenase |
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| Description: | |||||
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Similar to M. tuberculosis guaB3, Rv3410c, putative inosine-5'-monophosphate dehydrogenase, SW:YY10_MYCTU (Q50716) (375 aa); Fasta score E(): 0, 90.5% identity in 368 aa overlap. This ORF is similar in part to ML0387 and ML2066, which more closely resemble the experimentally characterised IMP-DH's (e.g. from Escherichia coli). This shorter homologue is conserved in several bacterial genera. Previously sequenced as SW:YY10_MYCLE (U00015) (375 aa); Fasta score E(): 0, 100.0% identity in 370 aa overlap. Contains Pfam match to entry PF00478 IMPDH_C, IMP dehydrogenase / GMP reductase C terminus., Shows weak similarity to ML0387 and ML2066 |
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| Translation: | |||||
MGRVARRTYE
LREISIVPSR
RTRSSKDVST
AWQLDAYRFE
IPVVAHPTDA
LVSPEFAIEL
GRLGGLGVLN
GEGLIGRHAD
VGAKVAQLIE
AAEKEPEPAT
AVCLLQELHA
APLNPDLLGS
AVARIREAGV
TTAVRVSPQN
AQVLTPVLLA
AGIDLLVVQG
SIVSAECVAS
GGEPLNLKTF
ISELDVPVVA
GGVLDHRTAL
HLMRTGAAGV
IVGYGSTRGA
TTSDEVLGIS
VPMATAIADA
AAARREYLDE
TGGRYVHVLA
DGDIYTSGEL
AKAIACGADA
VVLGTPLAQS
AEALGGGWFW
PAAAAHPSLP
RGALLQTAVG
ERPSLQQVLN
GPSDNPFGTL
NLVGGLRRSM
AKAGYCDLKE
FQKVGLIVSI
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| Pfam domains present: | |||||
Pfam match to entry PF00478 IMPDH_C, IMP dehydrogenase / GMP reductase C terminus, score -16.40, E-value 3.7e-06
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| Prosite patterns present: | |||||
None
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Last Modified Thu Oct 23 12:50:17 2003
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