| Gene name: | Class: | Start/End: | Length: | Molecular weight: | |
|---|---|---|---|---|---|
| folK | ML0226 | I.G.2 | 297941 / 298516 | 576 bp / 191 aa | 20761 Da |
| Product: | |||||
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putative 2-amino-4-hydroxy-6-hydroxymethyldihydropterine pyrophosphokinase |
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| Description: | |||||
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Similar to M. tuberculosis folK, Rv3607c, probable 2-amino-4-hydroxy-6-hydroxymethyldihydropterine pyrophosphokinase, SW:HPPK_MYCTU (O06276) (188 aa); Fasta score E(): 0, 63.2% identity in 190 aa overlap. Similar to others e.g. to the C-terminal half of Streptococcus pneumoniae sulD, bifunctional folate synthesis protein (includes: dihydroneopterin aldolase and 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase), SW:SULD_STRPN (P22291) (270 aa); Fasta score E(): 1.8e-07, 37.8% identity in 135 aa overlap. Previously sequenced as SW:HPPK_MYCLE (O69528) (191 aa); Fasta score E(): 0, 100.0% identity in 191 aa overlap. Contains Pfam match to entry PF01288 HPPK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Contains PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. |
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| Translation: | |||||
MTRVVLSIGS
NLGDRLAWLQ
SAVDGLGDAV
VAVSPVYDTV
PWGAVEQRSF
LNAVVIADGP
AYDTKAWLCR
AQELERNAGR
VRGQRWGART
LDVDLISCYQ
TSGATTGAVE
VITCESNLTL
PHPRAHLRAF
VLVPWLAVDS
DAELTVAGRA
QRVDRLLAEM
EPTEREGVRL
TNLTLKLKRS
SPARPVSPKS
D
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| Pfam domains present: | |||||
Pfam match to entry PF01288 HPPK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK), score 246.10, E-value 1.5e-70
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| Prosite patterns present: | |||||
PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature
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Last Modified Thu Oct 23 12:50:10 2003
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