Circular representation of the C. diphtheriae NCTC13129 chromosome.

From the outer to the inner circle: Circle 1, DNA bases (counting clockwise); circles 2 and 3, all genes (forward and reverse strands); circle 4, PAIs; circle 5, genes with orthologues in M. tuberculosis; circle 6, metal-ion transport systems (orange), phage-related genes (navy blue), DT (black); circle 7, putative sortases (red), putative sortase substrates (green); circle 8, repX (brown), IS element pairs (purple); circle 9, G+C content (plotted using a 10 kb window); circle 10, GC skew [(G-C) / (G+C)] (plotted using a 10 kb window).

Colour coding for circles 2, 3 and 5: dark blue, pathogenicity/adaptation; black, energy metabolism; red, information transfer; dark green, surface associated; cyan, degradation of large molecules; magenta, degradation of small molecules; yellow, central/intermediary metabolism; pale green, unknown; pale blue, regulators; orange, conserved hypothetical; brown, pseudogenes; pink, phage and IS elements; grey, miscellaneous.

From: Cerdeño-Tárraga et al. (2003)NAR, 31(22):6516-6523.

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