Burkholderia cenocepacia J2315
Image source: Emma Ralph and Eshwar Mahenthiralingam, Cardiff School of Biosciences, University of Cardiff, UK	Schematic circular diagrams of the Burkholderia cenocepacia J2315 genome from Holden et al. (2009) Journal of Bacteriology.

The Sanger Institute has completed the sequencing of and recently published the 8.06 Mb genome of Burkholderia cenocepacia strain J2315, in collaboration with Dr. Eshwar Mahenthiralingham of the School of Biosciences, Cardiff University, Prof. John Govan of the Department of Medical Microbiology, University of Edinburgh, Prof. C.A. Hart of the Department of Medical Microbiology, University of Liverpool, and Prof. Peter Vandamme of the Laboratorium voor Microbiologie, Universiteit Gent, Belgium.

Burkholderia cenocepacia (formerly Burkholderia cepacia genomovar III, and before that Pseudomonas cepacia) is a Gram negative bacterium which is ubiquitous in the environment and may cause a number of diseases in plants. Human infection can be caused by B. cepacia, especially in patients with cystic fibrosis and chronic granulomatous disease, and is often fatal. The strain to be sequenced, J2315, is a genomovar III strain of the ET12 lineage, and is the index strain for transmission of this strain among CF patients in the UK. Strain J2315 has been deposited as LMG 16656 in the Belgium Coordinated Collection of Microorganisms.

Note that B. cenocepacia J2315 has recently been renamed from B. cepacia J2315. Information about this change is published in Vandamme et al. (2003) Res Microbiol. 154 91-96

		Burkholderia cenocepacia J2315 Data     The complete Chromosome 1 sequence and annotation in Artemis format.     The complete Chromosome 2 sequence and annotation in Artemis format.     The complete Chromosome 3 sequence and annotation in Artemis format.     The complete plasmid sequence and annotation in Artemis format.     A BLAST server allowing searching of the chromosome sequences and predicted CDSs.     FTP access to the sequences and CDS databases.

The databases are available for searching on our Blast Server, or for download from our FTP site.

The sequence and annotation of the Burkholderia cenocepacia strain J2315 genome have been deposited in the EMBL database under accession numbers AM747720, AM747721, AM747722, and AM747723.

Reference:

"The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of cystic fibrosis patients" (2009) Journal of Bacteriology 191:261-277.

Matthew T.G. Holden, Helena M.B. Seth-Smith, Lisa C. Crossman, Mohammed Sebaihia, Stephen D. Bentley, Ana M. Cerdeño-Tárraga, Nicholas R. Thomson, Nathalie Bason, Michael A. Quail, Sarah Sharp, Inna Cherevach, Carol Churcher, Ian Goodhead, Heidi Hauser, Nancy Holroyd, Karen Mungall, Paul Scott, Danielle Walker, Brian White, Helen Rose, Pernille Iversen, Dalila Mil-Homens, Eduardo P.C. Rocha, Arsenio M. Fialho, Adam Baldwin, Christopher Dowson, Bart G. Barrell, John R. Govan, Peter Vandamme, C. Anthony Hart, Eshwar Mahenthiralingam and Julian Parkhill.