We have been granted a strategic award from the Wellcome Trust 'The Homunculus in our Thymus: A Cellular Genomics Approach' that enables us to investigate how thymic epithelial cells (TEC) - irrespective of their cell identity - remarkably can express virtually the complete set of protein-coding genes. These studies are relevant to better understand the fundamental function of the immune system and to identify causes of autoimmune diseases.
Programmes, Associate Research Programmes and Facilities
We are focused on using single-cell approaches, so called “cell atlas” technologies and understanding human genetics at the cellular level. The team combine cutting-edge techniques in wet and dry lab and are applying these methodologies for further understanding of human health, development and disease.
Our aim is to offer a high-quality, high-throughput single cell sequencing service that enables Faculty to study and understand cellular heterogeneity and it’s role in health and disease. We further want to create a collaborative and open environment to foster single cell method development.
Thierry Voet's group focuses on developing methods that characterise the DNA and RNA in a single cell to enable the exploration of DNA-mutation, the genetic differences between cells in a person's body and the relation of this diversity to disease.