Cellular Generation and Phenotyping | Scientific Operations

Cellular Generation and Phenotyping | Scientific Operations

Cellular Generation and Phenotyping

cgapteam.jpg

Our Research and Approach

The Cellular Generation and Phenotyping (CGaP) core facility provides central cell biology support to the Sanger Institute, in particular the scale-up of existing protocols to facilitate 'Science at Scale'. CGaP takes a unique approach at the institute by partnering with faculty groups in order to deliver large scale projects. We function as a contract research group for the insitute, running multiple, distinct cell biology based projects. The facility has expertise in cell derivation from primary tissue, iPSC and organoid derivation, cellular differentiation, CRISPR library screens, phenotypic assays and end point analysis (e.g. Immunocytochemistry) and functional bioassays.

If you are interested in obtaining a degree level apprenticeship in the field of Cell Biology then CGaP are offering this opportunity for 1 successful candidate in 2019. The application process will open on the 1st February via https://www.findapprenticeship.service.gov.uk/apprenticeshipsearch

Read More

People

Dr Rachel Nelson
Group Leader

Head of CGaP, Cellular Generation & Phenotyping Core Facility

Govan, Ceri

Govan, Ceri
Ceri Govan
Principal Technical Assistant

Key Projects, Collaborations, Tools & Data

The team are currently involved with a number of major projects at the Sanger Institute including HiPSCi (www.hipsci.org) and INSIGNIA (http://www.mutationsignatures.org/insignia/). In addition, CGaP have grants independently of faculty programs with EBISC to produce iPS cells and with the MRC to work on next-generation stem cell culture systems.

Partners and Funders

CGaP currently have a number of external grants both independantly and as part of WTSI programs. Staff on WSTI programs are funded via grants from the MRC and from core funded from the Wellcome Trust. In addition CGaP have grants independatly of faculty programs with EBISC to produce iPS cells and with the MRC to work on next generation stem cell culture systems.
Internal Partners
External Partners and Funders

Publications

  • Successful Generation of Human Induced Pluripotent Stem Cell Lines from Blood Samples Held at Room Temperature for up to 48 hr.

    Agu CA, Soares FA, Alderton A, Patel M, Ansari R et al.

    Stem cell reports 2015;5;4;660-71