GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Systemic lupus erythematosus

The human homologues of the following genes have been identified in "Systemic lupus erythematosus" studies:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
A5PMT7_DANRE LAMC2 ENSDARG00000068288 1 Not determined 2
AFF1 AFF1 ENSDARG00000086044 1 Not determined 4
ARID5B ARID5B ENSDARG00000037196 2 Not determined 7
atg5 ATG5 ENSDARG00000023396 2 Not determined 2
bach2 BACH2 ENSDARG00000004074 2 Not determined 14
bltk BLK ENSDARG00000007783 2 Not determined 11
CD44 (1 of 2) CD44 ENSDARG00000089892 None Not determined 4
cdkn1b CDKN1B ENSDARG00000054271 None Not determined 1
cdkn1bl CDKN1B ENSDARG00000029018 None Not determined 1
COL25A1 (2 of 2) COL25A1 ENSDARG00000022620 None Not determined 1
COL25A1 (1 of 2) COL25A1 ENSDARG00000068218 2 Not determined 1
crebl2 CREBL2 ENSDARG00000094623 None Not determined 1
dda1 DDA1 ENSDARG00000076074 1 Not determined 1
dguok DGUOK ENSDARG00000051983 None Not determined 2
dguok DGUOK ENSDARG00000075395 None Not determined 2
dram1 DRAM1 ENSDARG00000045561 2 Not determined 1
ghra GHR ENSDARG00000054771 2 Not determined 2
ghrb GHR ENSDARG00000007671 None Not determined 2
gpr19 GPR19 ENSDARG00000041125 None Not determined 1
hic1l HIC2 ENSDARG00000045660 1 Not determined 1
ikzf1 IKZF1 ENSDARG00000013539 4 Not determined 10
irf5 IRF5 ENSDARG00000045681 None Not determined 14
ITGAM ITGAX ENSDARG00000002956 2 Not determined 1
ITGAM ITGAM ENSDARG00000002956 2 Not determined 5
lef1 LEF1 ENSDARG00000031894 4 Not determined 3
LOC557210 BACH2 ENSDARG00000036569 4 Not determined 14
LOC558703 SOCS6 ENSDARG00000058565 None Not determined 1
LOC568967 LRRC18 ENSDARG00000076236 None Not determined 2
mhc2dab HLA-DRB1 ENSDARG00000079105 None Not determined 35
NAALADL2 NAALADL2 ENSDARG00000086489 2 Not determined 4
negr1 NEGR1 ENSDARG00000021607 1 Not determined 6
NEGR1 (2 of 2) NEGR1 ENSDARG00000091309 None Not determined 6
NP_001038387.1 SCN10A ENSDARG00000059692 6 Not determined 8
NP_001091732.1 HLA-DRB1 ENSDARG00000071168 1 Not determined 35
NP_997957.1 CDKN1B ENSDARG00000088081 None Not determined 1
ntm NEGR1 ENSDARG00000018065 1 Not determined 6
NTNG2 (2 of 2) NTNG2 ENSDARG00000087100 3 Not determined 1
prdm1a PRDM1 ENSDARG00000002445 3 Not determined 3
prdm1b PRDM1 ENSDARG00000053592 5 Not determined 3
prdm1c PRDM1 ENSDARG00000078161 None Not determined 3
pxk PXK ENSDARG00000063195 2 Not determined 2
rasgrp3 RASGRP3 ENSDARG00000077864 1 Not determined 3
rtkn2 RTKN2 ENSDARG00000053558 2 Not determined 3
si:busm1-104n07.3 HLA-DRB1 ENSDARG00000074510 1 Normal 35
si:busm1-160c18.1 HLA-DQA2 ENSDARG00000053739 2 Not determined 17
si:busm1-160c18.1 HLA-DQA1 ENSDARG00000053739 2 Not determined 27
si:busm1-160c18.3 HLA-DRB1 ENSDARG00000053738 None Not determined 35
si:busm1-160c18.3 HLA-DRB1 ENSDARG00000093706 None Not determined 35
si:busm1-194e12.11 HLA-DQA2 ENSDARG00000055441 1 Not determined 17
si:busm1-194e12.11 HLA-DQA1 ENSDARG00000055441 1 Not determined 27
si:busm1-194e12.12 HLA-DRB1 ENSDARG00000055447 None Not determined 35
si:busm1-228j01.3 HLA-DQA2 ENSDARG00000086294 2 Not determined 17
si:busm1-228j01.3 HLA-DQA1 ENSDARG00000086294 2 Not determined 27
si:busm1-228j01.4 HLA-DRB1 ENSDARG00000088872 2 Not determined 35
si:busm1-228j01.5 HLA-DQA1 ENSDARG00000079593 3 Not determined 27
si:busm1-228j01.5 HLA-DQA2 ENSDARG00000079593 3 Not determined 17
si:busm1-228j01.6 HLA-DRB1 ENSDARG00000041705 1 Not determined 35
si:ch1073-403i13.1 HLA-DQA2 ENSDARG00000001832 None Not determined 17
si:ch1073-403i13.1 HLA-DQA1 ENSDARG00000001832 None Not determined 27
si:ch211-195h3.2 NTNG2 ENSDARG00000077367 9 Not determined 1
si:ch211-220a11.1 TET3 ENSDARG00000062646 3 Not determined 2
si:ch211-232m8.6 PTTG1 ENSDARG00000075421 None Not determined 2
si:ch211-274c22.6 TNFAIP3 ENSDARG00000027777 5 Not determined 11
si:ch73-116b16.2 SLC1A7 ENSDARG00000026248 None Not determined 2
si:ch73-211l2.3 HLA-DQA1 ENSDARG00000075932 1 Not determined 27
si:ch73-211l2.3 HLA-DQA2 ENSDARG00000075932 1 Not determined 17
si:ch73-90n13.2 UHRF1BP1 ENSDARG00000077011 3 Not determined 2
si:dkey-192o1.2 PTTG1 ENSDARG00000090991 None Not determined 2
si:dkey-229d2.2 TMC2 ENSDARG00000030311 2 Not determined 2
si:dkey-267i17.6 TMC2 ENSDARG00000033104 2 Not determined 2
si:dkey-27a13.1 COL25A1 ENSDARG00000093421 2 Not determined 1
si:dkey-282h22.6 SEZ6L2 ENSDARG00000076052 7 Not determined 2
si:dkey-37h18.2 SLC29A3 ENSDARG00000077828 None Not determined 3
si:dkey-70o15.2 WDFY4 ENSDARG00000077009 8 Not determined 4
si:dkey-70o15.3 LRRC18 ENSDARG00000078790 None Not determined 2
si:dkeyp-2h4.2 HLA-DQA1 ENSDARG00000031745 None Not determined 27
si:dkeyp-2h4.2 HLA-DQA2 ENSDARG00000031745 None Not determined 17
si:zfos-2070c2.1 HLA-DQA2 ENSDARG00000070206 None Not determined 17
si:zfos-2070c2.1 HLA-DQA1 ENSDARG00000070206 None Not determined 27
si:zfos-2070c2.3 HLA-DRB1 ENSDARG00000076307 None Not determined 35
si:zfos-367g9.1 HLA-DQA1 ENSDARG00000074816 1 Not determined 27
si:zfos-367g9.1 HLA-DQA2 ENSDARG00000074816 1 Not determined 17
slc1a7a SLC1A7 ENSDARG00000034940 1 Not determined 2
slc1a8a SLC1A7 ENSDARG00000034628 2 Not determined 2
slc1a8b SLC1A7 ENSDARG00000032465 None Not determined 2
socs6b SOCS6 ENSDARG00000015863 None Not determined 1
stat4 STAT4 ENSDARG00000028731 3 Not determined 19
tnip1 TNIP1 ENSDARG00000015653 2 Not determined 6
tnpo3 TNPO3 ENSDARG00000045680 4 Not determined 7
tnxb TNXB ENSDARG00000001760 5 Not determined 4
ube2l3a UBE2L3 ENSDARG00000019188 None Not determined 8
ube2l3b UBE2L3 ENSDARG00000027141 1 Not determined 8
wu:fa99e04 CD44 ENSDARG00000087863 2 Not determined 4
wu:fd58b11 HLA-DRB1 ENSDARG00000054921 None Not determined 35
zgc:123107 HLA-DQA2 ENSDARG00000020286 None Not determined 17
zgc:123107 HLA-DQA1 ENSDARG00000020286 None Not determined 27
zgc:153067 HLA-DRB1 ENSDARG00000056330 2 Not determined 35
zgc:158706 ARID5B ENSDARG00000069988 None Not determined 7
zgc:56230 CLEC16A ENSDARG00000038094 3 Not determined 13
zgc:63767 SLC15A4 ENSDARG00000000384 4 Not determined 2
zgc:77151 ARID5B ENSDARG00000054307 1 Not determined 7

The following reported genes could not be linked automatically to a zebrafish gene:

  • APOBEC4
  • BANK1
  • BANK1
  • c10orf64
  • C6orf10
  • C8orf13
  • CD80
  • ELF1
  • ELF1
  • ETS1
  • ETS1
  • ETS1
  • HLA region
  • HLA-DR3
  • KIAA1542
  • KIAA1542
  • NOTCH4
  • OR4A15
  • RPL7AP59
  • TNFSF4
  • TNFSF4
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