GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Major depressive disorder

The human homologues of the following genes have been identified in "Major depressive disorder" studies:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
adcyap1r1 ADCYAP1R1 ENSDARG00000029989 1 Not determined 1
alg3 ALG3 ENSDARG00000053155 2 Not determined 1
ampd2 AMPD2 ENSDARG00000029952 6 Normal 1
ap2m1a AP2M1 ENSDARG00000002790 2 Not determined 1
ap2m1b AP2M1 ENSDARG00000033899 1 Not determined 1
atxn1a ATXN1 ENSDARG00000061687 1 Not determined 3
atxn1b ATXN1 ENSDARG00000060862 None Not determined 3
atxn7l2a ATXN7L2 ENSDARG00000055300 2 Not determined 2
atxn7l2b ATXN7L2 ENSDARG00000056268 1 Not determined 2
B1H1M8_DANRE PARP15 ENSDARG00000075426 None Not determined 1
btr01 RFPL4A ENSDARG00000051965 4 Not determined 1
btr02 RFPL4A ENSDARG00000052215 1 Not determined 1
btr04 RFPL4A ENSDARG00000060962 1 Not determined 1
btr05 RFPL4A ENSDARG00000074813 2 Not determined 1
btr06 RFPL4A ENSDARG00000054184 None Not determined 1
btr07p RFPL4A ENSDARG00000094877 1 Not determined 1
btr09 RFPL4A ENSDARG00000054805 1 Not determined 1
btr12 RFPL4A ENSDARG00000051809 2 Not determined 1
btr16 RFPL4A ENSDARG00000028850 1 Not determined 1
btr20 RFPL4A ENSDARG00000075603 1 Not determined 1
btr21 RFPL4A ENSDARG00000094915 None Not determined 1
btr22 RFPL4A ENSDARG00000093049 None Not determined 1
btr24 RFPL4A ENSDARG00000093340 None Not determined 1
btr26 RFPL4A ENSDARG00000040860 2 Not determined 1
btr27 RFPL4A ENSDARG00000095500 4 Not determined 1
btr29 RFPL4A ENSDARG00000002046 1 Not determined 1
btr30 RFPL4A ENSDARG00000090028 1 Not determined 1
btr32 RFPL4A ENSDARG00000053940 None Not determined 1
C2orf71 C2orf71 ENSDARG00000037656 1 Not determined 1
ca16b PTPRG ENSDARG00000060123 5 Not determined 5
calml4 CALML4 ENSDARG00000059347 2 Not determined 1
camk2n1a CAMK2N2 ENSDARG00000025855 None Not determined 1
ccnd2a CCND2 ENSDARG00000051748 None Not determined 7
ccnd2b CCND2 ENSDARG00000070408 None Not determined 7
ccnh CCNH ENSDARG00000007657 None Not determined 1
chst8 CHST8 ENSDARG00000044577 1 Normal 3
CHST8 (1 of 2) CHST8 ENSDARG00000074560 None Not determined 3
cln6 CLN6 ENSDARG00000077584 2 Not determined 1
CLN6 (2 of 2) CLN6 ENSDARG00000090002 1 Not determined 1
cyb561d1 CYB561D1 ENSDARG00000055295 1 Not determined 3
dmrt1 DMRT1 ENSDARG00000007349 2 Not determined 4
dmrt3a DMRT3 ENSDARG00000035290 2 Not determined 1
dsel DSEL ENSDARG00000061461 1 Not determined 2
dvl3 DVL3 ENSDARG00000015707 4 Not determined 1
ece1 ECE2 ENSDARG00000087841 3 Not determined 2
ehhadh EHHADH ENSDARG00000070029 2 Normal 2
eif2b5 EIF2B5 ENSDARG00000074995 1 Not determined 1
EIF2B5 (2 of 2) EIF2B5 ENSDARG00000086151 None Not determined 1
enox1 ENOX1 ENSDARG00000060243 1 Not determined 3
epn1 EPN1 ENSDARG00000010411 4 Not determined 1
esrrd ESRRG ENSDARG00000015064 None Not determined 4
esrrga ESRRG ENSDARG00000004861 3 Not determined 4
esrrgb ESRRG ENSDARG00000011696 None Not determined 4
FBXO31 FBXO31 ENSDARG00000062195 4 Not determined 1
fem1b FEM1B ENSDARG00000062636 1 Not determined 1
fgf12 FGF12 ENSDARG00000027957 None Not determined 3
fhit FHIT ENSDARG00000068850 None Not determined 9
fhit FHIT ENSDARG00000078195 None Not determined 9
fmn1 FMN1 ENSDARG00000011975 5 Not determined 2
FMN1 (2 of 3) FMN1 ENSDARG00000086384 1 Not determined 2
gdnf GDNF ENSDARG00000039959 None Not determined 1
gmpr GMPR ENSDARG00000016160 2 Not determined 4
gnai1 GNAI3 ENSDARG00000021647 None Not determined 1
gnai3 GNAI3 ENSDARG00000030644 1 Not determined 1
gnaia GNAI3 ENSDARG00000044760 None Not determined 1
gnat2 GNAT2 ENSDARG00000094180 2 Not determined 1
GRIN2B (2 of 2) GRIN2B ENSDARG00000079348 3 Not determined 6
grin2bb GRIN2B ENSDARG00000030376 4 Not determined 6
homer1 HOMER1 ENSDARG00000007517 None Not determined 2
HOMER1 (1 of 3) HOMER1 ENSDARG00000073803 1 Not determined 2
igfbp1a IGFBP1 ENSDARG00000014947 None Not determined 1
igfbp1b IGFBP1 ENSDARG00000038666 None Not determined 1
igfbp3 IGFBP3 ENSDARG00000014859 1 Not determined 3
itga11a ITGA11 ENSDARG00000036086 3 Not determined 2
itga11b ITGA11 ENSDARG00000007950 3 Not determined 2
kcnh5a KCNH5 ENSDARG00000043220 4 Not determined 2
KCTD15 KCTD15 ENSDARG00000058255 None Not determined 5
kctd15a KCTD15 ENSDARG00000045893 None Not determined 5
laptm4a LAPTM4A ENSDARG00000006397 1 Not determined 1
LOC100148950 FMN1 ENSDARG00000088133 None Not determined 2
LOC100149082 DVL3 ENSDARG00000002148 1 Not determined 1
LOC100329239 FAM38B ENSDARG00000076005 None Not determined 3
LOC100329307 DSEL ENSDARG00000074504 1 Not determined 2
LOC100331227 ABCF3 ENSDARG00000089705 1 Not determined 1
LOC100333588 HTR3D ENSDARG00000074824 None Not determined 1
LOC100333588 HTR3C ENSDARG00000074824 None Not determined 1
LOC100333588 HTR3E ENSDARG00000074824 None Not determined 1
LOC100333796 HTR3C ENSDARG00000078428 1 Not determined 1
LOC100333796 HTR3E ENSDARG00000078428 1 Not determined 1
LOC100333796 HTR3D ENSDARG00000078428 1 Not determined 1
LOC555473 ADCYAP1R1 ENSDARG00000053724 1 Not determined 1
LOC556805 RFPL4A ENSDARG00000090930 None Not determined 1
LOC558290 SYPL2 ENSDARG00000037587 1 Not determined 2
LOC559232 RGS9BP ENSDARG00000086756 None Not determined 1
LOC559388 CNIH4 ENSDARG00000087759 None Not determined 1
LOC559461 WDR26 ENSDARG00000062310 3 Not determined 1
LOC567794 WBSCR17 ENSDARG00000042418 4 Not determined 2
LOC571944 RFPL4A ENSDARG00000090371 None Not determined 1
LOC799840 RFPL4A ENSDARG00000008164 2 Not determined 1
lysmd4 LYSMD4 ENSDARG00000068702 None Not determined 1
map1lc3b MAP1LC3B ENSDARG00000020048 None Not determined 1
mrpl14 MRPL14 ENSDARG00000068886 1 Not determined 2
mylipa MYLIP ENSDARG00000008859 1 Not determined 3
mylipb MYLIP ENSDARG00000055118 None Not determined 3
myo10l2 MYO10 ENSDARG00000017004 6 Not determined 3
myo10l3 MYO10 ENSDARG00000074143 11 Not determined 3
ncana VCAN ENSDARG00000067820 2 Not determined 1
ncanb VCAN ENSDARG00000005783 1 Not determined 1
nlgn1 NLGN1 ENSDARG00000077710 1 Not determined 1
NP_001002496.2 HOMER1 ENSDARG00000018108 None Not determined 2
NP_571944.1 GNAT2 ENSDARG00000042529 2 Not determined 1
nvl NVL ENSDARG00000025605 2 Not determined 1
pard3 PARD3 ENSDARG00000010583 10 Not determined 4
PARD3 (2 of 2) PARD3 ENSDARG00000091238 2 Not determined 4
parp12b PARP9 ENSDARG00000057974 None Not determined 1
parp12b PARP15 ENSDARG00000057974 None Not determined 1
PARP14 PARP15 ENSDARG00000074139 5 Not determined 1
pcdh1 PCDH1 ENSDARG00000036175 6 Not determined 2
pdcd5 PDCD5 ENSDARG00000026072 2 Not determined 1
pias1 PIAS1 ENSDARG00000036094 4 Not determined 1
ptprga PTPRG ENSDARG00000045006 6 Not determined 5
rasa1 RASA1 ENSDARG00000035535 6 Not determined 2
rasgef1ba RASGEF1B ENSDARG00000033614 2 Not determined 2
rasgef1bb RASGEF1B ENSDARG00000044251 4 Not determined 2
rgs9bp RGS9BP ENSDARG00000009466 1 Not determined 1
si:busm1-163l24.3 DTX3L ENSDARG00000056469 2 Not determined 1
si:ch211-103a14.2 AMPD2 ENSDARG00000088554 None Not determined 1
si:ch211-114c12.5 RFPL4A ENSDARG00000092931 None Not determined 1
si:ch211-153j24.6 WDR26 ENSDARG00000006812 4 Not determined 1
si:ch211-154h20.4 SLC6A15 ENSDARG00000062821 1 Not determined 1
si:ch211-219a4.3 PARP15 ENSDARG00000040445 None Not determined 1
si:ch211-219a4.6 PARP9 ENSDARG00000006848 1 Not determined 1
si:ch211-251m13.1 KCNH5 ENSDARG00000069117 6 Not determined 2
si:ch211-255l14.7 ZCCHC14 ENSDARG00000012738 2 Not determined 1
si:ch211-89p1.4 C9orf98 ENSDARG00000030961 3 Not determined 2
si:dkey-11f4.7 FAM38B ENSDARG00000074800 4 Not determined 3
si:dkey-11p6.1 CPM ENSDARG00000011769 1 Not determined 1
si:dkey-169a9.2 RASA1 ENSDARG00000073665 2 Not determined 2
si:dkey-18f22.3 PCDH1 ENSDARG00000062720 2 Not determined 2
si:dkey-18p12.4 RFPL4A ENSDARG00000079703 1 Not determined 1
si:dkey-206d17.10 RFPL4A ENSDARG00000093290 None Not determined 1
si:dkey-206d17.7 RFPL4A ENSDARG00000013481 None Not determined 1
si:dkey-22o12.2 C3orf70 ENSDARG00000091513 3 Not determined 1
si:dkey-29b22.6 SLC6A15 ENSDARG00000007129 3 Not determined 1
si:dkey-9i9.1 PIAS1 ENSDARG00000062445 None Not determined 1
sod3 SOD3 ENSDARG00000079183 None Not determined 1
sod3 SOD3 ENSDARG00000094543 None Not determined 1
sp4 SP4 ENSDARG00000005186 1 Not determined 3
synpr SYPL2 ENSDARG00000044278 None Not determined 2
sypl2a SYPL2 ENSDARG00000055307 2 Not determined 2
sypl2b SYPL2 ENSDARG00000000690 3 Not determined 2
tigara C12orf5 ENSDARG00000051749 4 Not determined 3
tigarb C12orf5 ENSDARG00000045858 None Not determined 3
trps1 TRPS1 ENSDARG00000068028 3 Not determined 4
vcana VCAN ENSDARG00000078680 14 Normal 1
vcanb VCAN ENSDARG00000009401 10 Normal 1
vwa5b2 VWA5B2 ENSDARG00000075886 5 Normal 1
wu:fc41e04 ANKRD27 ENSDARG00000089207 1 Not determined 1
zgc:103502 CCND2 ENSDARG00000027391 None Not determined 7
zgc:109913 RGS9BP ENSDARG00000022512 None Not determined 1
zgc:110585 SCHIP1 ENSDARG00000035175 None Not determined 3
zgc:153120 FGF12 ENSDARG00000062542 None Not determined 3
zgc:153615 SCHIP1 ENSDARG00000038981 None Not determined 3
zgc:162707 C3orf70 ENSDARG00000061664 1 Not determined 1
zgc:162925 SLC6A15 ENSDARG00000037422 3 Not determined 1
zgc:165473 SOD3 ENSDARG00000070168 1 Not determined 1
zgc:193500 CALML4 ENSDARG00000075800 None Not determined 1
zgc:194225 NUDT19 ENSDARG00000077537 None Not determined 2
zgc:194578 EPN1 ENSDARG00000079847 2 Not determined 1
zgc:194990 RFPL4A ENSDARG00000069407 1 Not determined 1
zgc:63948 NDFIP2 ENSDARG00000033928 1 Not determined 2
zgc:92198 CAMK2N2 ENSDARG00000090424 None Not determined 1

The following reported genes could not be linked automatically to a zebrafish gene:

  • C12orf36
  • C15orf51
  • FAM179A
  • FLJ41603
  • IL12A
  • LOC647167
  • LOC728275
  • MIR1224
  • MIR548D2
  • MIR548D2
  • NLRP11
  • NLRP9
  • PCLO
  • SHC4
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