GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Coronary heart disease

The human homologues of the following genes have been identified in "Coronary heart disease" studies:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
A4IGH1_DANRE RASD1 ENSDARG00000026383 None Not determined 1
A5PMT7_DANRE LAMC2 ENSDARG00000068288 1 Not determined 2
A5WWE7_DANRE ALDH2 ENSDARG00000037094 None Not determined 12
abca1a ABCA1 ENSDARG00000074635 9 Not determined 13
ALDH2 (3 of 4) ALDH2 ENSDARG00000090766 1 Not determined 12
aldh2a ALDH2 ENSDARG00000089924 None Not determined 12
aldh2b ALDH2 ENSDARG00000028087 None Not determined 12
anks1a ANKS1A ENSDARG00000062396 4 Not determined 4
ANKS1A (2 of 2) ANKS1A ENSDARG00000078901 1 Not determined 4
apoa1 APOA5 ENSDARG00000012076 1 Not determined 22
apoa1 APOA4 ENSDARG00000012076 1 Not determined 11
apoa1 APOA1 ENSDARG00000012076 1 Not determined 13
apoa4 APOA4 ENSDARG00000040298 1 Not determined 11
apoa4 APOA1 ENSDARG00000040298 1 Not determined 13
apoa4 APOA5 ENSDARG00000040298 1 Not determined 22
atp2b1a ATP2B1 ENSDARG00000012684 2 Not determined 6
atp2b1b ATP2B1 ENSDARG00000007788 7 Not determined 6
BTNL2 BTNL2 ENSDARG00000093039 1 Not determined 18
C12orf51 (3 of 3) C12orf51 ENSDARG00000090715 None Not determined 9
C12orf51 (1 of 3) C12orf51 ENSDARG00000079151 5 Not determined 9
cdkn2b CDKN2A ENSDARG00000037262 2 Not determined 25
cdkn2b CDKN2B ENSDARG00000037262 2 Not determined 30
celsr1a CELSR2 ENSDARG00000069185 8 Not determined 17
CELSR2 CELSR2 ENSDARG00000088231 4 Not determined 17
celsr2l CELSR2 ENSDARG00000019726 2 Not determined 17
cetp CETP ENSDARG00000030872 2 Not determined 27
cnnm2a CNNM2 ENSDARG00000061195 2 Not determined 9
cnnm2b CNNM2 ENSDARG00000078733 1 Not determined 9
col4a1 COL4A1 ENSDARG00000055009 7 Not determined 3
col4a2 COL4A2 ENSDARG00000020781 5 Not determined 2
CSMD1 CSMD1 ENSDARG00000058353 3 Not determined 12
cxcl12a CXCL12 ENSDARG00000037116 2 Not determined 4
cxcl12b CXCL12 ENSDARG00000055100 4 Not determined 4
cyp17a1 CYP17A1 ENSDARG00000033566 3 Not determined 7
cyp17a2 CYP17A1 ENSDARG00000053966 None Not determined 7
dnm2 DNM2 ENSDARG00000069937 9 Not determined 1
DNM2 (2 of 2) DNM2 ENSDARG00000020270 3 Not determined 1
DOCK6 DOCK6 ENSDARG00000035706 7 Normal 2
dtnb DTNB ENSDARG00000013020 5 Not determined 3
dtng DTNB ENSDARG00000077694 None Not determined 3
edc4 EDC4 ENSDARG00000062266 4 Not determined 2
flt1 FLT1 ENSDARG00000019371 8 Normal 2
grinl1a GCOM1 ENSDARG00000075017 1 Not determined 1
gucy1a3 GUCY1A3 ENSDARG00000013787 None Not determined 3
hhipl1 HHIPL1 ENSDARG00000062501 3 Not determined 1
hnf1a HNF1A ENSDARG00000009470 None Not determined 21
IGSF5 (2 of 2) IGSF5 ENSDARG00000090953 1 Not determined 1
KIAA1462 (2 of 2) KIAA1462 ENSDARG00000088405 5 Not determined 2
KLHL29 (1 of 2) KLHL29 ENSDARG00000087688 4 Not determined 3
ldlr LDLR ENSDARG00000029476 3 Not determined 15
LDLR (2 of 2) LDLR ENSDARG00000089730 None Not determined 15
lipf LIPA ENSDARG00000018529 None Not determined 2
LOC100001168 KIAA1462 ENSDARG00000089871 6 Not determined 2
LOC100330423 C12orf51 ENSDARG00000003682 4 Not determined 9
LOC100334314 KLHL29 ENSDARG00000043799 5 Not determined 3
LOC100334463 PLEKHO2 ENSDARG00000016774 None Not determined 1
LOC793137 LCAT ENSDARG00000062375 None Not determined 6
mia3 MIA3 ENSDARG00000008184 2 Not determined 3
morf4l1 MORF4L1 ENSDARG00000041155 1 Not determined 1
mtap MTAP ENSDARG00000037261 1 Not determined 3
myl2 MYL2 ENSDARG00000053424 None Not determined 4
MYL2 (2 of 2) MYL2 ENSDARG00000043349 None Not determined 4
NP_956003.1 DTNB ENSDARG00000037388 None Not determined 3
nt5c2a NT5C2 ENSDARG00000039399 3 Not determined 9
nt5c2b NT5C2 ENSDARG00000058231 2 Not determined 9
oprm1 OPRM1 ENSDARG00000039434 None Not determined 1
PCSK9 PCSK9 ENSDARG00000074185 1 Not determined 10
PDGFD PDGFD ENSDARG00000077677 3 Not determined 3
pemt PEMT ENSDARG00000040450 None Not determined 1
plg LPA ENSDARG00000023111 7 Not determined 10
ppap2b PPAP2B ENSDARG00000059933 None Not determined 4
ppp1r3b PPP1R3B ENSDARG00000044691 None Not determined 9
Q5SP03_DANRE MIA3 ENSDARG00000095703 None Not determined 3
rasd1 RASD1 ENSDARG00000019274 None Not determined 1
sb:cb1008 CUX2 ENSDARG00000086559 2 Not determined 2
SH2B3 (1 of 2) SH2B3 ENSDARG00000069958 None Not determined 19
si:ch211-136a13.1 HHIPL1 ENSDARG00000060927 1 Not determined 1
si:ch211-198b3.2 FNDC1 ENSDARG00000002847 3 Not determined 1
si:ch211-206k20.4 WDR35 ENSDARG00000069269 4 Not determined 1
si:ch211-218i18.2 CUX2 ENSDARG00000086345 None Not determined 2
si:ch211-231m12.2 IGSF5 ENSDARG00000087983 None Not determined 1
si:ch73-386h18.1 ZFHX3 ENSDARG00000073944 7 Not determined 7
si:dkey-159a18.1 SORT1 ENSDARG00000056145 1 Not determined 13
si:dkey-242g16.2 PPP1R3B ENSDARG00000069377 None Not determined 9
si:dkey-258f14.3 LDLR ENSDARG00000075974 None Not determined 15
si:dkey-25e12.5 MTHFD1L ENSDARG00000042221 4 Not determined 3
si:dkey-30k22.7 CELSR2 ENSDARG00000037286 4 Not determined 17
si:dkey-7f3.15 APOA4 ENSDARG00000094929 3 Not determined 11
si:dkey-7f3.15 APOA1 ENSDARG00000094929 3 Not determined 13
si:dkey-7f3.15 APOA5 ENSDARG00000094929 3 Not determined 22
si:dkeyp-1e8.2 SH2B3 ENSDARG00000093095 None Not determined 19
si:dkeyp-50f7.3 TTC32 ENSDARG00000069241 None Not determined 1
si:rp71-1n18.3 MRAS ENSDARG00000062865 None Not determined 2
si:rp71-1n18.3 MRAS ENSDARG00000075285 None Not determined 2
slc12a9 SLC12A9 ENSDARG00000060366 3 Not determined 3
slc30a1 SLC30A1 ENSDARG00000005463 2 2 normal 1
smad3a SMAD3 ENSDARG00000036096 2 Not determined 5
smad3b SMAD3 ENSDARG00000010207 2 Not determined 5
smarca4 SMARCA4 ENSDARG00000077226 2 Not determined 1
SMARCA4 (2 of 2) SMARCA4 ENSDARG00000008350 3 Not determined 1
smg6 SMG6 ENSDARG00000075957 2 Not determined 5
snf8 SNF8 ENSDARG00000058076 None Not determined 1
sort1a SORT1 ENSDARG00000029402 1 Not determined 13
sort1b SORT1 ENSDARG00000056252 10 Not determined 13
tcf21 TCF21 ENSDARG00000036869 None Not determined 2
tcf7l2 TCF7L2 ENSDARG00000004415 5 Not determined 23
tnika TNIK ENSDARG00000056218 5 Not determined 2
tnikb TNIK ENSDARG00000009031 3 Not determined 2
vegfaa VEGFA ENSDARG00000045971 None Not determined 8
vegfab VEGFA ENSDARG00000034700 None Not determined 8
wdr12 WDR12 ENSDARG00000003287 1 Not determined 2
zc3hc1 ZC3HC1 ENSDARG00000062651 1 Not determined 1
ZFHX3 ZFHX3 ENSDARG00000073681 11 Not determined 7
zgc:112992 APOA4 ENSDARG00000086281 None Not determined 11
zgc:112992 APOA1 ENSDARG00000086281 None Not determined 13
zgc:112992 APOA5 ENSDARG00000086281 None Not determined 22
zgc:113271 RNF130 ENSDARG00000022389 1 Not determined 1
zgc:114118 RASD1 ENSDARG00000052222 None Not determined 1
zgc:152698 RASD1 ENSDARG00000058464 None Not determined 1
zgc:153039 SLC12A9 ENSDARG00000060524 None Not determined 3
zgc:153390 MRPS6 ENSDARG00000039543 None Not determined 2
zgc:153845 RASD1 ENSDARG00000012772 None Not determined 1
zgc:158309 PPAP2B ENSDARG00000069940 7 Not determined 4
zgc:162025 C12orf43 ENSDARG00000046141 None Not determined 4
zgc:162909 SLC30A1 ENSDARG00000053896 2 Not determined 1
zgc:171581 ABCA1 ENSDARG00000079009 7 Not determined 13
zgc:175176 SLC22A3 ENSDARG00000058775 1 Not determined 5
zgc:194131 APOA4 ENSDARG00000020866 2 Not determined 11
zgc:194131 APOA1 ENSDARG00000020866 2 Not determined 13
zgc:194131 APOA5 ENSDARG00000020866 2 Not determined 22
zgc:73293 ATP5G1 ENSDARG00000056008 None Not determined 1
zgc:77112 PPP1R3B ENSDARG00000015657 None Not determined 9
zgc:85777 ACAD10 ENSDARG00000027009 2 Normal 3
zgc:92375 FHL5 ENSDARG00000014805 5 Not determined 2
zgc:92419 UBE2Z ENSDARG00000029215 1 Not determined 1
znf259 ZNF259 ENSDARG00000043542 2 Not determined 11

The following reported genes could not be linked automatically to a zebrafish gene:

  • ABO
  • ABO
  • ADAMTS7
  • ADAMTS7
  • ADAMTS7
  • APOC3
  • C6orf10
  • CDKN2A/2B
  • CDKN2A/B
  • DRB-DQB
  • FN
  • GIP
  • HCG27
  • HLA
  • HLA-C
  • ILR6
  • LPAL2
  • LPAL2
  • PHACTR1
  • PHACTR1
  • PHACTR1
  • PHACTR1
  • PHACTR1
  • PHACTR1
  • PHACTR1
  • PHACTR1
  • PSRC1
  • PSRC1
  • RPL6-PTPN11
  • SMCR3
  • SRR
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