GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Asthma

The human homologues of the following genes have been identified in "Asthma" studies:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
aco1 ACO1 ENSDARG00000026376 4 Not determined 1
BTNL2 BTNL2 ENSDARG00000093039 1 Not determined 18
cdk2 CDK2 ENSDARG00000026577 2 Not determined 3
crb1 CRB1 ENSDARG00000062245 7 Normal 1
D1LXJ4_DANRE PRKG1 ENSDARG00000031702 2 Not determined 2
gab1 GAB1 ENSDARG00000037018 1 Not determined 1
il2rb IL2RB ENSDARG00000075720 3 Not determined 3
il6r IL6R ENSDARG00000070398 2 Not determined 7
im:6906849 RAD50 ENSDARG00000038917 6 Not determined 2
LOC100000685 SLC22A5 ENSDARG00000068603 1 Not determined 5
LOC100002134 SLC30A8 ENSDARG00000054584 1 Not determined 16
LOC100007362 PCDH20 ENSDARG00000036424 2 Not determined 4
LOC560642 SLC30A8 ENSDARG00000057629 None Not determined 16
LOC799279 IL1R1 ENSDARG00000090844 None Not determined 2
LOC799279 IL1RL1 ENSDARG00000090844 None Not determined 8
mhc2dab HLA-DQB1 ENSDARG00000079105 None Not determined 24
ndfip1 NDFIP1 ENSDARG00000013979 None Not determined 4
ndfip1l NDFIP1 ENSDARG00000008057 None Not determined 4
NP_001091732.1 HLA-DQB1 ENSDARG00000071168 1 Not determined 24
ntla T ENSDARG00000009905 1 Not determined 2
ntlb T ENSDARG00000039806 2 Not determined 2
pbx2 PBX2 ENSDARG00000019717 None Not determined 2
PBX2 (1 of 2) PBX2 ENSDARG00000092447 None Not determined 2
pbx3a PBX2 ENSDARG00000093513 None Not determined 2
pde4d PDE4D ENSDARG00000032761 6 Not determined 7
prkg1a PRKG1 ENSDARG00000020656 1 Not determined 2
Q7ZW49_DANRE PBX2 ENSDARG00000086991 1 Not determined 2
roraa RORA ENSDARG00000031768 2 Not determined 11
rorab RORA ENSDARG00000001910 2 Not determined 11
scg3 SCG3 ENSDARG00000086288 1 Not determined 1
si:busm1-104n07.3 HLA-DQB1 ENSDARG00000074510 1 Normal 24
si:busm1-160c18.1 HLA-DOA ENSDARG00000053739 2 Not determined 2
si:busm1-160c18.1 HLA-DQA1 ENSDARG00000053739 2 Not determined 27
si:busm1-160c18.1 HLA-DQA2 ENSDARG00000053739 2 Not determined 17
si:busm1-160c18.1 HLA-DRA ENSDARG00000053739 2 Not determined 21
si:busm1-160c18.3 HLA-DQB1 ENSDARG00000053738 None Not determined 24
si:busm1-160c18.3 HLA-DQB1 ENSDARG00000093706 None Not determined 24
si:busm1-194e12.11 HLA-DQA2 ENSDARG00000055441 1 Not determined 17
si:busm1-194e12.11 HLA-DRA ENSDARG00000055441 1 Not determined 21
si:busm1-194e12.11 HLA-DOA ENSDARG00000055441 1 Not determined 2
si:busm1-194e12.11 HLA-DQA1 ENSDARG00000055441 1 Not determined 27
si:busm1-194e12.12 HLA-DQB1 ENSDARG00000055447 None Not determined 24
si:busm1-228j01.3 HLA-DQA2 ENSDARG00000086294 2 Not determined 17
si:busm1-228j01.3 HLA-DRA ENSDARG00000086294 2 Not determined 21
si:busm1-228j01.3 HLA-DOA ENSDARG00000086294 2 Not determined 2
si:busm1-228j01.3 HLA-DQA1 ENSDARG00000086294 2 Not determined 27
si:busm1-228j01.4 HLA-DQB1 ENSDARG00000088872 2 Not determined 24
si:busm1-228j01.5 HLA-DQA2 ENSDARG00000079593 3 Not determined 17
si:busm1-228j01.5 HLA-DRA ENSDARG00000079593 3 Not determined 21
si:busm1-228j01.5 HLA-DOA ENSDARG00000079593 3 Not determined 2
si:busm1-228j01.5 HLA-DQA1 ENSDARG00000079593 3 Not determined 27
si:busm1-228j01.6 HLA-DQB1 ENSDARG00000041705 1 Not determined 24
si:ch1073-403i13.1 HLA-DRA ENSDARG00000001832 None Not determined 21
si:ch1073-403i13.1 HLA-DOA ENSDARG00000001832 None Not determined 2
si:ch1073-403i13.1 HLA-DQA1 ENSDARG00000001832 None Not determined 27
si:ch1073-403i13.1 HLA-DQA2 ENSDARG00000001832 None Not determined 17
si:ch1073-409b12.4 SLC22A5 ENSDARG00000094112 None Not determined 5
si:ch211-195i21.1 DENND1B ENSDARG00000029374 1 Not determined 3
si:ch211-69e5.1 CRB1 ENSDARG00000079519 4 Not determined 1
si:ch73-211l2.3 HLA-DQA2 ENSDARG00000075932 1 Not determined 17
si:ch73-211l2.3 HLA-DRA ENSDARG00000075932 1 Not determined 21
si:ch73-211l2.3 HLA-DOA ENSDARG00000075932 1 Not determined 2
si:ch73-211l2.3 HLA-DQA1 ENSDARG00000075932 1 Not determined 27
si:ch73-211p17.2 LRRC32 ENSDARG00000040621 None Not determined 2
si:dkey-121j17.5 PRKG1 ENSDARG00000014232 6 Not determined 2
si:dkey-166n8.9 IKZF4 ENSDARG00000037068 None Not determined 5
si:dkey-27i16.3 PCDH20 ENSDARG00000057773 9 Not determined 4
si:dkeyp-2h4.2 HLA-DQA2 ENSDARG00000031745 None Not determined 17
si:dkeyp-2h4.2 HLA-DRA ENSDARG00000031745 None Not determined 21
si:dkeyp-2h4.2 HLA-DOA ENSDARG00000031745 None Not determined 2
si:dkeyp-2h4.2 HLA-DQA1 ENSDARG00000031745 None Not determined 27
si:zfos-2070c2.1 HLA-DQA2 ENSDARG00000070206 None Not determined 17
si:zfos-2070c2.1 HLA-DRA ENSDARG00000070206 None Not determined 21
si:zfos-2070c2.1 HLA-DOA ENSDARG00000070206 None Not determined 2
si:zfos-2070c2.1 HLA-DQA1 ENSDARG00000070206 None Not determined 27
si:zfos-2070c2.3 HLA-DQB1 ENSDARG00000076307 None Not determined 24
si:zfos-367g9.1 HLA-DQA2 ENSDARG00000074816 1 Not determined 17
si:zfos-367g9.1 HLA-DRA ENSDARG00000074816 1 Not determined 21
si:zfos-367g9.1 HLA-DOA ENSDARG00000074816 1 Not determined 2
si:zfos-367g9.1 HLA-DQA1 ENSDARG00000074816 1 Not determined 27
slc22a4 SLC22A5 ENSDARG00000005335 2 Not determined 5
smad3a SMAD3 ENSDARG00000036096 2 Not determined 5
smad3b SMAD3 ENSDARG00000010207 2 Not determined 5
wu:fd58b11 HLA-DQB1 ENSDARG00000054921 None Not determined 24
zgc:101654 ORMDL3 ENSDARG00000025555 1 Not determined 14
zgc:123107 HLA-DQA2 ENSDARG00000020286 None Not determined 17
zgc:123107 HLA-DRA ENSDARG00000020286 None Not determined 21
zgc:123107 HLA-DOA ENSDARG00000020286 None Not determined 2
zgc:123107 HLA-DQA1 ENSDARG00000020286 None Not determined 27
zgc:153067 HLA-DQB1 ENSDARG00000056330 2 Not determined 24

The following reported genes could not be linked automatically to a zebrafish gene:

  • C11orf71
  • C5orf56
  • C6orf10
  • CRCT1
  • DPB1
  • GSDMA
  • GSDMB
  • GSDMB
  • HLA
  • HLA-DQ
  • IL13
  • IL18R1
  • IL18R1
  • IL18R1
  • IL33
  • IL33
  • KIAA1271
  • LOC338591
  • LOC729675
  • NOTCH4
  • PYHIN1
  • TSLP
  • TSLP
  • ZNF665
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