GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Alzheimer's disease (late onset)

The human homologues of the following genes have been identified in "Alzheimer's disease (late onset)" studies:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
apoeb APOE ENSDARG00000040295 1 Not determined 42
ATXN7L1 ATXN7L1 ENSDARG00000089860 1 Not determined 3
bcl3 BCL3 ENSDARG00000087832 4 Not determined 1
bin1 BIN1 ENSDARG00000058820 3 Not determined 6
cd2apl CD2AP ENSDARG00000015224 3 Not determined 1
cdon CDON ENSDARG00000061328 5 Not determined 1
ceacam1 CEACAM16 ENSDARG00000041119 2 Not determined 1
clu CLU ENSDARG00000010434 None Not determined 5
cxcr3.1 CEACAM16 ENSDARG00000078177 None Not determined 1
gab2 GAB2 ENSDARG00000074577 1 Not determined 2
LOC560512 PVRL2 ENSDARG00000077419 None Not determined 9
LOC560816 PVRL2 ENSDARG00000062831 None Not determined 9
LOC798358 MS4A4A ENSDARG00000091970 2 Not determined 1
LOC798679 MS4A4A ENSDARG00000095695 1 Not determined 1
ms4a17a.1 MS4A4A ENSDARG00000043798 None Not determined 1
ms4a17a.11 MS4A4A ENSDARG00000053561 None Not determined 1
ms4a17a.14 MS4A4A ENSDARG00000094809 None Not determined 1
ms4a17a.2 MS4A4A ENSDARG00000093546 4 Not determined 1
ms4a17a.4 MS4A4A ENSDARG00000014024 3 Not determined 1
ms4a17a.5 MS4A4A ENSDARG00000092204 2 Not determined 1
ms4a17a.6 MS4A4A ENSDARG00000007018 1 Not determined 1
ms4a17a.7 MS4A4A ENSDARG00000043796 None Not determined 1
ms4a17a.8 MS4A4A ENSDARG00000094854 1 Not determined 1
ms4a17a.9 MS4A4A ENSDARG00000043802 2 Not determined 1
ms4a17c.1 MS4A4A ENSDARG00000094643 None Not determined 1
ms4a17c.2 MS4A4A ENSDARG00000028659 None Not determined 1
pcnx PCNX ENSDARG00000011819 6 Not determined 1
picalm PICALM ENSDARG00000012866 1 Not determined 5
picalml PICALM ENSDARG00000014137 2 Not determined 5
pvrl2l PVRL2 ENSDARG00000063390 1 Not determined 9
pvrl4 PVRL2 ENSDARG00000094356 None Not determined 9
si:ch211-141e20.2 PVRL2 ENSDARG00000093349 None Not determined 9
si:ch211-214p13.3 PVRL2 ENSDARG00000087403 1 Not determined 9
si:ch211-222f23.6 PVRL2 ENSDARG00000042880 1 Not determined 9
si:ch211-243k12.1 LUZP2 ENSDARG00000068247 1 Not determined 5
si:ch211-264f5.6 CEACAM16 ENSDARG00000079372 2 Not determined 1
si:ch73-132m10.4 MS4A4A ENSDARG00000054898 3 Not determined 1
si:dkey-11o1.2 CEACAM16 ENSDARG00000095772 None Not determined 1
si:dkey-11o1.3 CEACAM16 ENSDARG00000093279 1 Not determined 1
si:dkey-174k12.3 MS4A4A ENSDARG00000092593 None Not determined 1
si:dkey-238j22.1 MS4A4A ENSDARG00000093512 None Not determined 1
si:dkey-250k15.10 CEACAM16 ENSDARG00000092520 None Not determined 1
si:dkey-250k15.7 CEACAM16 ENSDARG00000095048 None Not determined 1
si:dkey-250k15.9 CEACAM16 ENSDARG00000095134 None Not determined 1
si:dkey-25e12.5 MTHFD1L ENSDARG00000042221 4 Not determined 3
si:dkey-281i8.1 PVRL2 ENSDARG00000069936 None Not determined 9
si:dkey-78k11.2 CR1 ENSDARG00000095512 None Not determined 5
si:rp71-68g1.4 BIN1 ENSDARG00000042114 3 Not determined 6
SORL1 SORL1 ENSDARG00000013892 7 Normal 2
tomm40 TOMM40 ENSDARG00000092112 1 Not determined 23
tomm40l TOMM40 ENSDARG00000036721 None Not determined 23
zgc:110064 APOE ENSDARG00000086370 1 Not determined 42
zgc:110608 MPZL1 ENSDARG00000059048 None Not determined 1
zgc:110775 CR1 ENSDARG00000056075 1 Not determined 5
zgc:172302 ABCA7 ENSDARG00000074221 4 Not determined 2
zgc:198329 CEACAM16 ENSDARG00000076981 1 Not determined 1

The following reported genes could not be linked automatically to a zebrafish gene:

  • CD33
  • CUGBP2
  • EPHA1
  • PPP1R37
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