GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
acaca ACACA ENSDARG00000078512 5 Not determined 1
chmp4c CHMP4C ENSDARG00000007418 None Not determined 1
dusp14 DUSP14 ENSDARG00000057625 1 Not determined 1
fabp11a PMP2 ENSDARG00000090113 None Not determined 1
fabp11a FABP12 ENSDARG00000090113 None Not determined 1
fabp11a FABP5 ENSDARG00000090113 None Not determined 1
fabp11a FABP4 ENSDARG00000090113 None Not determined 2
fabp11b PMP2 ENSDARG00000002311 1 Not determined 1
fabp11b FABP12 ENSDARG00000002311 1 Not determined 1
fabp11b FABP5 ENSDARG00000002311 1 Not determined 1
fabp11b FABP4 ENSDARG00000002311 1 Not determined 2
GPR179 (1 of 2) GPR179 ENSDARG00000090995 None Not determined 1
hnf1ba HNF1B ENSDARG00000006615 1 Not determined 8
hnf1bb HNF1B ENSDARG00000022295 None Not determined 8
impa1 IMPA1 ENSDARG00000003517 2 Not determined 1
LOC100150565 DUSP14 ENSDARG00000088800 None Not determined 1
LOC100334189 FABP5 ENSDARG00000088621 None Not determined 1
LOC100334189 FABP4 ENSDARG00000088621 None Not determined 2
LOC100334189 PMP2 ENSDARG00000088621 None Not determined 1
LOC100334189 FABP12 ENSDARG00000088621 None Not determined 1
LOC570339 GPR179 ENSDARG00000076643 None Not determined 1
mllt10 MLLT10 ENSDARG00000045401 None Not determined 2
mrpl45 MRPL45 ENSDARG00000044942 None Not determined 1
myca MYC ENSDARG00000045695 None Not determined 7
mycb MYC ENSDARG00000007241 None Not determined 7
mych MYC ENSDARG00000077473 None Not determined 7
NP_001004682.1 FABP5 ENSDARG00000017299 None Not determined 1
NP_001004682.1 FABP4 ENSDARG00000017299 None Not determined 2
NP_001004682.1 PMP2 ENSDARG00000017299 None Not determined 1
NP_001004682.1 FABP12 ENSDARG00000017299 None Not determined 1
si:ch1073-184j22.2 DUSP14 ENSDARG00000078598 2 Not determined 1
si:ch211-288d18.1 TBC1D3 ENSDARG00000011088 1 Not determined 1
si:ch211-288d18.1 TBC1D3F ENSDARG00000011088 1 Not determined 1
si:dkey-24h18.1 ARHGAP23 ENSDARG00000026840 5 Not determined 1
si:dkeyp-19e1.3 TBC1D3F ENSDARG00000051836 1 Not determined 1
si:dkeyp-19e1.3 TBC1D3 ENSDARG00000051836 1 Not determined 1
socs7 SOCS7 ENSDARG00000077018 None Not determined 1
socs7 SOCS7 ENSDARG00000090553 None Not determined 1
SYNRG SYNRG ENSDARG00000073926 3 Not determined 2
tada2a TADA2A ENSDARG00000031562 3 Not determined 1
zfand1 ZFAND1 ENSDARG00000009178 None Not determined 1
zgc:152779 DNAJC1 ENSDARG00000001940 None Not determined 1
zgc:77396 SNX16 ENSDARG00000046072 None Not determined 3

The following reported genes could not be linked automatically to a zebrafish gene:

  • C10orf113
  • C10orf113
  • C10orf114
  • C10orf114
  • C17orf78
  • DDX52
  • NEBL
  • NEBL
  • SKIDA1
  • SKIDA1
  • SLC10A5
  • SLC10A5
Short-link