GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
atxn1a ATXN1 ENSDARG00000061687 1 Not determined 3
atxn1b ATXN1 ENSDARG00000060862 None Not determined 3
btr01 RFPL4A ENSDARG00000051965 4 Not determined 1
btr02 RFPL4A ENSDARG00000052215 1 Not determined 1
btr04 RFPL4A ENSDARG00000060962 1 Not determined 1
btr05 RFPL4A ENSDARG00000074813 2 Not determined 1
btr06 RFPL4A ENSDARG00000054184 None Not determined 1
btr07p RFPL4A ENSDARG00000094877 1 Not determined 1
btr09 RFPL4A ENSDARG00000054805 1 Not determined 1
btr12 RFPL4A ENSDARG00000051809 2 Not determined 1
btr16 RFPL4A ENSDARG00000028850 1 Not determined 1
btr20 RFPL4A ENSDARG00000075603 1 Not determined 1
btr21 RFPL4A ENSDARG00000094915 None Not determined 1
btr22 RFPL4A ENSDARG00000093049 None Not determined 1
btr24 RFPL4A ENSDARG00000093340 None Not determined 1
btr26 RFPL4A ENSDARG00000040860 2 Not determined 1
btr27 RFPL4A ENSDARG00000095500 4 Not determined 1
btr29 RFPL4A ENSDARG00000002046 1 Not determined 1
btr30 RFPL4A ENSDARG00000090028 1 Not determined 1
btr32 RFPL4A ENSDARG00000053940 None Not determined 1
calml4 CALML4 ENSDARG00000059347 2 Not determined 1
ccnd2a CCND2 ENSDARG00000051748 None Not determined 7
ccnd2b CCND2 ENSDARG00000070408 None Not determined 7
ccnh CCNH ENSDARG00000007657 None Not determined 1
chst8 CHST8 ENSDARG00000044577 1 Normal 3
CHST8 (1 of 2) CHST8 ENSDARG00000074560 None Not determined 3
cln6 CLN6 ENSDARG00000077584 2 Not determined 1
CLN6 (2 of 2) CLN6 ENSDARG00000090002 1 Not determined 1
dmrt1 DMRT1 ENSDARG00000007349 2 Not determined 4
dmrt3a DMRT3 ENSDARG00000035290 2 Not determined 1
enox1 ENOX1 ENSDARG00000060243 1 Not determined 3
epn1 EPN1 ENSDARG00000010411 4 Not determined 1
esrrd ESRRG ENSDARG00000015064 None Not determined 4
esrrga ESRRG ENSDARG00000004861 3 Not determined 4
esrrgb ESRRG ENSDARG00000011696 None Not determined 4
fem1b FEM1B ENSDARG00000062636 1 Not determined 1
fgf12 FGF12 ENSDARG00000027957 None Not determined 3
fmn1 FMN1 ENSDARG00000011975 5 Not determined 2
FMN1 (2 of 3) FMN1 ENSDARG00000086384 1 Not determined 2
gmpr GMPR ENSDARG00000016160 2 Not determined 4
GRIN2B (2 of 2) GRIN2B ENSDARG00000079348 3 Not determined 6
grin2bb GRIN2B ENSDARG00000030376 4 Not determined 6
igfbp1a IGFBP1 ENSDARG00000014947 None Not determined 1
igfbp1b IGFBP1 ENSDARG00000038666 None Not determined 1
igfbp3 IGFBP3 ENSDARG00000014859 1 Not determined 3
itga11a ITGA11 ENSDARG00000036086 3 Not determined 2
itga11b ITGA11 ENSDARG00000007950 3 Not determined 2
kcnh5a KCNH5 ENSDARG00000043220 4 Not determined 2
KCTD15 KCTD15 ENSDARG00000058255 None Not determined 5
kctd15a KCTD15 ENSDARG00000045893 None Not determined 5
LOC100148950 FMN1 ENSDARG00000088133 None Not determined 2
LOC100329239 FAM38B ENSDARG00000076005 None Not determined 3
LOC556805 RFPL4A ENSDARG00000090930 None Not determined 1
LOC559232 RGS9BP ENSDARG00000086756 None Not determined 1
LOC567794 WBSCR17 ENSDARG00000042418 4 Not determined 2
LOC571944 RFPL4A ENSDARG00000090371 None Not determined 1
LOC799840 RFPL4A ENSDARG00000008164 2 Not determined 1
lysmd4 LYSMD4 ENSDARG00000068702 None Not determined 1
mrpl14 MRPL14 ENSDARG00000068886 1 Not determined 2
mylipa MYLIP ENSDARG00000008859 1 Not determined 3
mylipb MYLIP ENSDARG00000055118 None Not determined 3
myo10l2 MYO10 ENSDARG00000017004 6 Not determined 3
myo10l3 MYO10 ENSDARG00000074143 11 Not determined 3
pcdh1 PCDH1 ENSDARG00000036175 6 Not determined 2
pdcd5 PDCD5 ENSDARG00000026072 2 Not determined 1
pias1 PIAS1 ENSDARG00000036094 4 Not determined 1
rasa1 RASA1 ENSDARG00000035535 6 Not determined 2
rasgef1ba RASGEF1B ENSDARG00000033614 2 Not determined 2
rasgef1bb RASGEF1B ENSDARG00000044251 4 Not determined 2
rgs9bp RGS9BP ENSDARG00000009466 1 Not determined 1
si:ch211-114c12.5 RFPL4A ENSDARG00000092931 None Not determined 1
si:ch211-251m13.1 KCNH5 ENSDARG00000069117 6 Not determined 2
si:ch211-89p1.4 C9orf98 ENSDARG00000030961 3 Not determined 2
si:dkey-11f4.7 FAM38B ENSDARG00000074800 4 Not determined 3
si:dkey-169a9.2 RASA1 ENSDARG00000073665 2 Not determined 2
si:dkey-18f22.3 PCDH1 ENSDARG00000062720 2 Not determined 2
si:dkey-18p12.4 RFPL4A ENSDARG00000079703 1 Not determined 1
si:dkey-206d17.10 RFPL4A ENSDARG00000093290 None Not determined 1
si:dkey-206d17.7 RFPL4A ENSDARG00000013481 None Not determined 1
si:dkey-9i9.1 PIAS1 ENSDARG00000062445 None Not determined 1
sod3 SOD3 ENSDARG00000079183 None Not determined 1
sod3 SOD3 ENSDARG00000094543 None Not determined 1
tigara C12orf5 ENSDARG00000051749 4 Not determined 3
tigarb C12orf5 ENSDARG00000045858 None Not determined 3
wu:fc41e04 ANKRD27 ENSDARG00000089207 1 Not determined 1
zgc:103502 CCND2 ENSDARG00000027391 None Not determined 7
zgc:109913 RGS9BP ENSDARG00000022512 None Not determined 1
zgc:110585 SCHIP1 ENSDARG00000035175 None Not determined 3
zgc:153120 FGF12 ENSDARG00000062542 None Not determined 3
zgc:153615 SCHIP1 ENSDARG00000038981 None Not determined 3
zgc:165473 SOD3 ENSDARG00000070168 1 Not determined 1
zgc:193500 CALML4 ENSDARG00000075800 None Not determined 1
zgc:194225 NUDT19 ENSDARG00000077537 None Not determined 2
zgc:194578 EPN1 ENSDARG00000079847 2 Not determined 1
zgc:194990 RFPL4A ENSDARG00000069407 1 Not determined 1
zgc:63948 NDFIP2 ENSDARG00000033928 1 Not determined 2

The following reported genes could not be linked automatically to a zebrafish gene:

  • C12orf36
  • C15orf51
  • FLJ41603
  • IL12A
  • MIR548D2
  • MIR548D2
  • NLRP11
  • NLRP9
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