GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
arhgef3 ARHGEF3 ENSDARG00000013834 2 Not determined 6
arhgef3l ARHGEF3 ENSDARG00000037554 2 Not determined 6
atp2b4 ATP2B4 ENSDARG00000044902 3 Not determined 3
ba1l HBB ENSDARG00000089087 None Not determined 7
ba1l HBD ENSDARG00000089087 None Not determined 2
ba1l HBE1 ENSDARG00000089087 None Not determined 2
ba1l HBG1 ENSDARG00000089087 None Not determined 2
BAK1 (2 of 2) BAK1 ENSDARG00000089995 None Not determined 7
baxb BAK1 ENSDARG00000030881 None Not determined 7
bfb CFB ENSDARG00000005616 3 Not determined 6
bysl BYSL ENSDARG00000001057 None Not determined 3
cfb CFB ENSDARG00000055278 4 Not determined 6
cited2 CITED2 ENSDARG00000030905 None Not determined 5
cmyb MYB ENSDARG00000053666 2 Not determined 12
hbbe1.1 HBD ENSDARG00000089963 None Not determined 2
hbbe1.1 HBE1 ENSDARG00000089963 None Not determined 2
hbbe1.1 HBG1 ENSDARG00000089963 None Not determined 2
hbbe1.1 HBB ENSDARG00000089963 None Not determined 7
hbbe2 HBB ENSDARG00000045143 None Not determined 7
hbbe2 HBD ENSDARG00000045143 None Not determined 2
hbbe2 HBE1 ENSDARG00000045143 None Not determined 2
hbbe2 HBG1 ENSDARG00000045143 None Not determined 2
hbbe3 HBD ENSDARG00000038147 None Not determined 2
hbbe3 HBE1 ENSDARG00000038147 None Not determined 2
hbbe3 HBG1 ENSDARG00000038147 None Not determined 2
hbbe3 HBB ENSDARG00000038147 None Not determined 7
hbs1l HBS1L ENSDARG00000036778 1 Not determined 11
jmjd1c JMJD1C ENSDARG00000079939 5 Not determined 11
LOC571586 JMJD1C ENSDARG00000077805 10 Not determined 11
med20 MED20 ENSDARG00000046006 None Not determined 1
mhc1uba HFE ENSDARG00000075963 None Not determined 20
mhc1ze HFE ENSDARG00000074765 None Not determined 20
mhc1zel HFE ENSDARG00000092162 1 Not determined 20
mpp1 MPP1 ENSDARG00000031475 None Not determined 2
NP_919406.1 HFE ENSDARG00000086877 1 Not determined 20
Q1JPZ9_DANRE MUC21 ENSDARG00000079924 None Not determined 3
Q8MHB3_DANRE HFE ENSDARG00000076734 None Not determined 20
Q8MHB6_DANRE HFE ENSDARG00000088022 1 Not determined 20
rcl1 RCL1 ENSDARG00000038312 None Not determined 4
si:busm1-118j2.5 HBD ENSDARG00000087390 None Not determined 2
si:busm1-118j2.5 HBE1 ENSDARG00000087390 None Not determined 2
si:busm1-118j2.5 HBG1 ENSDARG00000087390 None Not determined 2
si:busm1-118j2.5 HBB ENSDARG00000087390 None Not determined 7
si:busm1-118j2.5 HBG1 ENSDARG00000090689 1 Not determined 2
si:busm1-118j2.5 HBB ENSDARG00000090689 1 Not determined 7
si:busm1-118j2.5 HBD ENSDARG00000090689 1 Not determined 2
si:busm1-118j2.5 HBE1 ENSDARG00000090689 1 Not determined 2
si:ch211-231a1.5 TMPRSS6 ENSDARG00000094087 None Not determined 14
si:ch211-287j19.6 HFE ENSDARG00000001470 2 Not determined 20
si:ch73-213j4.4 HFE ENSDARG00000092731 None Not determined 20
si:dkeyp-20g2.1 CCHCR1 ENSDARG00000092464 None Not determined 5
si:dkeyp-20g2.3 CCHCR1 ENSDARG00000093389 None Not determined 5
usp49 USP49 ENSDARG00000000229 None Not determined 1
zbtb12.2 ZBTB12 ENSDARG00000070658 2 Not determined 1
zgc:103502 CCND3 ENSDARG00000027391 None Not determined 6
zgc:136614 HFE ENSDARG00000069471 None Not determined 20
zgc:153993 BAK1 ENSDARG00000068102 None Not determined 7
zgc:158446 CFB ENSDARG00000090730 4 Not determined 6
zgc:64115 HFE ENSDARG00000036588 4 Not determined 20
zgc:92880 HBE1 ENSDARG00000069734 None Not determined 2
zgc:92880 HBG1 ENSDARG00000069734 None Not determined 2
zgc:92880 HBB ENSDARG00000069734 None Not determined 7
zgc:92880 HBD ENSDARG00000069734 None Not determined 2

The following reported genes could not be linked automatically to a zebrafish gene:

  • Alpha-globin cluster
  • Alpha-globin cluster
  • Alpha-globin cluster
  • Alpha-globin cluster
  • Alpha-globin cluster
  • Alpha-globin cluster
  • Alpha-globin cluster
  • Alpha-globin cluster
  • Alpha-globin cluster
  • ARHGEF3
  • BAK1
  • C6orf15
  • CDSN
  • COPZ1
  • DARC
  • DARC
  • HBBP1
  • HBBP1
  • HCG22
  • PSORS1C1
  • PSORS1C2
  • RCL1
  • STK19
  • TMPRSS6
  • TMPRSS6
  • TMPRSS6
Short-link