GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
cdc123 CDC123 ENSDARG00000075025 1 Not determined 5
cdkal1 CDKAL1 ENSDARG00000022122 2 Not determined 23
cdkn2b CDKN2B ENSDARG00000037262 2 Not determined 30
dusp7 DUSP9 ENSDARG00000032738 None Not determined 2
fam58a FAM58A ENSDARG00000037537 3 Not determined 1
glis3 GLIS3 ENSDARG00000069726 5 Not determined 6
hnf1ba HNF1B ENSDARG00000006615 1 Not determined 8
hnf1bb HNF1B ENSDARG00000022295 None Not determined 8
kcnq1 KCNQ1 ENSDARG00000059798 4 Not determined 15
KCNQ1 KCNQ1 ENSDARG00000091599 None Not determined 15

The following reported genes could not be linked automatically to a zebrafish gene:

  • GRK5
  • RASGRP1
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