GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

A genome-wide association study on a southern European population identifies a new Crohn's disease susceptibility locus at RBX1-EP300.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
atg16l1 ATG16L1 ENSDARG00000057430 None Not determined 8
card9 CARD9 ENSDARG00000067672 1 Not determined 9
crfb4 IFNGR2 ENSDARG00000068711 2 Not determined 3
D9IL85_DANRE IFNGR2 ENSDARG00000075776 None Not determined 3
ep300a EP300 ENSDARG00000062380 None Not determined 1
ep300a EP300 ENSDARG00000076430 None Not determined 1
ep300b EP300 ENSDARG00000061108 10 Not determined 1
foxp2 FOXP2 ENSDARG00000005453 7 Not determined 1
LOC799320 ZNF365 ENSDARG00000087985 1 Not determined 11
nod2 NOD2 ENSDARG00000010756 3 Not determined 10
ptger4a PTGER4 ENSDARG00000059236 2 Normal 12
ptger4b PTGER4 ENSDARG00000035415 1 Not determined 12
rbx1 RBX1 ENSDARG00000038030 None Not determined 1
si:ch211-234e14.2 PTGER4 ENSDARG00000079907 None Not determined 12
si:ch73-233m11.2 NOD2 ENSDARG00000091859 None Not determined 10
snapc4 SNAPC4 ENSDARG00000067673 1 Not determined 3

The following reported genes could not be linked automatically to a zebrafish gene:

  • AIF1
  • IL23R
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