GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
bach2 BACH2 ENSDARG00000004074 2 Not determined 14
casp7 CASP7 ENSDARG00000091836 None Not determined 1
CD44 (1 of 2) CD44 ENSDARG00000089892 None Not determined 4
CLNK CLNK ENSDARG00000091321 None Not determined 1
herc2 HERC2 ENSDARG00000073841 16 Not determined 5
ifih1 IFIH1 ENSDARG00000018553 1 Not determined 7
LOC100331324 CASP7 ENSDARG00000055550 None Not determined 1
LOC557210 BACH2 ENSDARG00000036569 4 Not determined 14
LOC798445 CASP7 ENSDARG00000054515 2 Not determined 1
NP_001038224.1 TICAM1 ENSDARG00000086136 None Not determined 1
oca2 OCA2 ENSDARG00000061303 5 Not determined 6
SH2B3 (1 of 2) SH2B3 ENSDARG00000069958 None Not determined 19
si:dkey-166n8.9 IKZF4 ENSDARG00000037068 None Not determined 5
si:dkeyp-1e8.2 SH2B3 ENSDARG00000093095 None Not determined 19
sla1 SLA ENSDARG00000054340 1 Not determined 2
ticam1 TICAM1 ENSDARG00000042714 None Not determined 1
TOB2 TOB2 ENSDARG00000074195 1 Not determined 1
tyr TYR ENSDARG00000039077 None Not determined 9
wu:fa99e04 CD44 ENSDARG00000087863 2 Not determined 4

The following reported genes could not be linked automatically to a zebrafish gene:

  • CD80
  • MC1R
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