GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association analysis implicates the involvement of eight loci with response to tocilizumab for the treatment of rheumatoid arthritis.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
enox1 ENOX1 ENSDARG00000060243 1 Not determined 3
etfa ETFA ENSDARG00000043944 None Not determined 1
mamdc1 MDGA2 ENSDARG00000024017 2 Not determined 3
MDGA2 (2 of 3) MDGA2 ENSDARG00000090441 None Not determined 3
MDGA2 (1 of 3) MDGA2 ENSDARG00000087310 None Not determined 3
psma4 PSMA4 ENSDARG00000045928 None Not determined 4
rchy1 RCHY1 ENSDARG00000016710 None Not determined 1
si:ch211-132b12.1 SLC6A11 ENSDARG00000061480 6 Not determined 1
si:ch211-132b12.2 SLC6A11 ENSDARG00000094946 1 Not determined 1
si:ch211-132b12.3 SLC6A11 ENSDARG00000068363 None Not determined 1
si:ch211-132b12.5 SLC6A11 ENSDARG00000068372 3 Not determined 1
si:ch211-132b12.6 SLC6A11 ENSDARG00000094546 1 Not determined 1
SLC6A11 SLC6A11 ENSDARG00000040435 None Not determined 1
slc6a11 SLC6A11 ENSDARG00000074002 3 Not determined 1
slc6a13 SLC6A11 ENSDARG00000000730 1 Not determined 1
slc6a13l SLC6A11 ENSDARG00000001354 5 Not determined 1
spsb1 SPSB1 ENSDARG00000056515 None Not determined 3
spsb4b SPSB1 ENSDARG00000040538 2 Not determined 3

The following reported genes could not be linked automatically to a zebrafish gene:

  • ENSG00000102921
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