GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

A genome-wide association study in Han Chinese identifies multiple susceptibility loci for IgA nephropathy.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
LOC100333801 MTMR3 ENSDARG00000089046 4 Not determined 6
mhc2dab HLA-DRB1 ENSDARG00000079105 None Not determined 35
mpdu1a MPDU1 ENSDARG00000035562 2 Not determined 1
mpdu1b MPDU1 ENSDARG00000040265 1 Not determined 1
NP_001091732.1 HLA-DRB1 ENSDARG00000071168 1 Not determined 35
NP_001161936.1 TNFSF13 ENSDARG00000091556 None Not determined 4
si:busm1-104n07.3 HLA-DRB1 ENSDARG00000074510 1 Normal 35
si:busm1-160c18.3 HLA-DRB1 ENSDARG00000053738 None Not determined 35
si:busm1-160c18.3 HLA-DRB1 ENSDARG00000093706 None Not determined 35
si:busm1-194e12.12 HLA-DRB1 ENSDARG00000055447 None Not determined 35
si:busm1-228j01.4 HLA-DRB1 ENSDARG00000088872 2 Not determined 35
si:busm1-228j01.6 HLA-DRB1 ENSDARG00000041705 1 Not determined 35
si:ch211-205h19.1 ACOXL ENSDARG00000020149 2 Not determined 6
si:ch73-100n10.1 MTMR3 ENSDARG00000093364 2 Not determined 6
si:zfos-2070c2.3 HLA-DRB1 ENSDARG00000076307 None Not determined 35
wu:fd58b11 HLA-DRB1 ENSDARG00000054921 None Not determined 35
zgc:153067 HLA-DRB1 ENSDARG00000056330 2 Not determined 35
zgc:77875 MTMR3 ENSDARG00000058305 2 Not determined 6

The following reported genes could not be linked automatically to a zebrafish gene:

  • DEFAs
  • HLA-A
  • HLA-DQA/B
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