GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

A genome-wide association study identifies two new risk loci for Graves' disease.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
bach2 BACH2 ENSDARG00000004074 2 Not determined 14
chrna9 CHRNA9 ENSDARG00000054680 2 1 phenotype, 1 normal 1
fgfr1op FGFR1OP ENSDARG00000003058 2 Not determined 2
LOC557210 BACH2 ENSDARG00000036569 4 Not determined 14
LOC798522 CHRNA9 ENSDARG00000011029 None Not determined 1
map3k7 MAP3K7 ENSDARG00000020469 2 Not determined 2
NP_001139235.1 TSHR ENSDARG00000037195 3 Not determined 4
Q1JPZ9_DANRE MUC21 ENSDARG00000079924 None Not determined 3
rhoh RHOH ENSDARG00000070121 None Not determined 1
rnaset2 RNASET2 ENSDARG00000036282 None Not determined 3
rnaset2l RNASET2 ENSDARG00000058413 None Not determined 3
si:ch211-160b7.1 CTLA4 ENSDARG00000095070 None Not determined 9
si:ch211-160b7.1 CD28 ENSDARG00000095070 None Not determined 2

The following reported genes could not be linked automatically to a zebrafish gene:

  • ABO
  • C6orf15
  • DPB1
  • DQA1
  • DQB1
  • DRB1
  • FCRL3
  • HLA
  • HLA
  • HLA-B
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