GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
A5PLF6_DANRE ADAD1 ENSDARG00000089181 3 Not determined 3
bach2 BACH2 ENSDARG00000004074 2 Not determined 14
cd226 CD226 ENSDARG00000045391 1 Not determined 5
erbb3a ERBB3 ENSDARG00000006202 1 Not determined 8
erbb3b ERBB3 ENSDARG00000036993 7 Not determined 8
ifih1 IFIH1 ENSDARG00000018553 1 Not determined 7
il10 IL10 ENSDARG00000078147 4 Normal 11
il2rb IL2RB ENSDARG00000075720 3 Not determined 3
ins INS ENSDARG00000035350 None Not determined 5
insb INS ENSDARG00000034610 None Not determined 5
LOC557210 BACH2 ENSDARG00000036569 4 Not determined 14
ptpn22 PTPN22 ENSDARG00000075062 5 Not determined 17
ptpn2a PTPN2 ENSDARG00000016481 4 Not determined 13
ptpn2b PTPN2 ENSDARG00000035986 2 Not determined 13
SH2B3 (1 of 2) SH2B3 ENSDARG00000069958 None Not determined 19
si:ch211-160b7.1 CTLA4 ENSDARG00000095070 None Not determined 9
si:dkey-166n8.9 IKZF4 ENSDARG00000037068 None Not determined 5
si:dkeyp-1e8.2 SH2B3 ENSDARG00000093095 None Not determined 19
TYK2 TYK2 ENSDARG00000020326 4 Not determined 6
zgc:101654 ORMDL3 ENSDARG00000025555 1 Not determined 14
zgc:56230 CLEC16A ENSDARG00000038094 3 Not determined 13

The following reported genes could not be linked automatically to a zebrafish gene:

  • FCRL3
  • IGF2AS
  • IL2
  • IL27
  • IL2RA
  • RASGRP1
  • UBASH3A
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