GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
BTNL2 BTNL2 ENSDARG00000093039 1 Not determined 18
cdk2 CDK2 ENSDARG00000026577 2 Not determined 3
gab1 GAB1 ENSDARG00000037018 1 Not determined 1
mhc2dab HLA-DQB1 ENSDARG00000079105 None Not determined 24
NP_001091732.1 HLA-DQB1 ENSDARG00000071168 1 Not determined 24
pbx2 PBX2 ENSDARG00000019717 None Not determined 2
PBX2 (1 of 2) PBX2 ENSDARG00000092447 None Not determined 2
pbx3a PBX2 ENSDARG00000093513 None Not determined 2
Q7ZW49_DANRE PBX2 ENSDARG00000086991 1 Not determined 2
si:busm1-104n07.3 HLA-DQB1 ENSDARG00000074510 1 Normal 24
si:busm1-160c18.1 HLA-DQA2 ENSDARG00000053739 2 Not determined 17
si:busm1-160c18.1 HLA-DRA ENSDARG00000053739 2 Not determined 21
si:busm1-160c18.1 HLA-DOA ENSDARG00000053739 2 Not determined 2
si:busm1-160c18.3 HLA-DQB1 ENSDARG00000053738 None Not determined 24
si:busm1-160c18.3 HLA-DQB1 ENSDARG00000093706 None Not determined 24
si:busm1-194e12.11 HLA-DQA2 ENSDARG00000055441 1 Not determined 17
si:busm1-194e12.11 HLA-DRA ENSDARG00000055441 1 Not determined 21
si:busm1-194e12.11 HLA-DOA ENSDARG00000055441 1 Not determined 2
si:busm1-194e12.12 HLA-DQB1 ENSDARG00000055447 None Not determined 24
si:busm1-228j01.3 HLA-DQA2 ENSDARG00000086294 2 Not determined 17
si:busm1-228j01.3 HLA-DRA ENSDARG00000086294 2 Not determined 21
si:busm1-228j01.3 HLA-DOA ENSDARG00000086294 2 Not determined 2
si:busm1-228j01.4 HLA-DQB1 ENSDARG00000088872 2 Not determined 24
si:busm1-228j01.5 HLA-DQA2 ENSDARG00000079593 3 Not determined 17
si:busm1-228j01.5 HLA-DRA ENSDARG00000079593 3 Not determined 21
si:busm1-228j01.5 HLA-DOA ENSDARG00000079593 3 Not determined 2
si:busm1-228j01.6 HLA-DQB1 ENSDARG00000041705 1 Not determined 24
si:ch1073-403i13.1 HLA-DQA2 ENSDARG00000001832 None Not determined 17
si:ch1073-403i13.1 HLA-DRA ENSDARG00000001832 None Not determined 21
si:ch1073-403i13.1 HLA-DOA ENSDARG00000001832 None Not determined 2
si:ch73-211l2.3 HLA-DOA ENSDARG00000075932 1 Not determined 2
si:ch73-211l2.3 HLA-DQA2 ENSDARG00000075932 1 Not determined 17
si:ch73-211l2.3 HLA-DRA ENSDARG00000075932 1 Not determined 21
si:dkey-166n8.9 IKZF4 ENSDARG00000037068 None Not determined 5
si:dkeyp-2h4.2 HLA-DOA ENSDARG00000031745 None Not determined 2
si:dkeyp-2h4.2 HLA-DQA2 ENSDARG00000031745 None Not determined 17
si:dkeyp-2h4.2 HLA-DRA ENSDARG00000031745 None Not determined 21
si:zfos-2070c2.1 HLA-DQA2 ENSDARG00000070206 None Not determined 17
si:zfos-2070c2.1 HLA-DRA ENSDARG00000070206 None Not determined 21
si:zfos-2070c2.1 HLA-DOA ENSDARG00000070206 None Not determined 2
si:zfos-2070c2.3 HLA-DQB1 ENSDARG00000076307 None Not determined 24
si:zfos-367g9.1 HLA-DRA ENSDARG00000074816 1 Not determined 21
si:zfos-367g9.1 HLA-DOA ENSDARG00000074816 1 Not determined 2
si:zfos-367g9.1 HLA-DQA2 ENSDARG00000074816 1 Not determined 17
wu:fd58b11 HLA-DQB1 ENSDARG00000054921 None Not determined 24
zgc:123107 HLA-DQA2 ENSDARG00000020286 None Not determined 17
zgc:123107 HLA-DRA ENSDARG00000020286 None Not determined 21
zgc:123107 HLA-DOA ENSDARG00000020286 None Not determined 2
zgc:153067 HLA-DQB1 ENSDARG00000056330 2 Not determined 24

The following reported genes could not be linked automatically to a zebrafish gene:

  • C6orf10
  • LOC338591
  • LOC729675
  • NOTCH4
  • TSLP
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