GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
arpc1b ARPC1A ENSDARG00000027063 None Not determined 1
cyp3a65 CYP3A43 ENSDARG00000045627 2 Not determined 1
cyp3c1 CYP3A43 ENSDARG00000015575 2 Not determined 1
cyp3c1l2 CYP3A43 ENSDARG00000037873 None Not determined 1
si:dkey-21n8.3 CYP3A43 ENSDARG00000037874 None Not determined 1
sult2st1 SULT2A1 ENSDARG00000033170 None Not determined 1
sult2st1 SULT2A1 ENSDARG00000086446 None Not determined 1
sult2st2 SULT2A1 ENSDARG00000053331 None Not determined 1
sult2st3 SULT2A1 ENSDARG00000028367 1 Not determined 1
zgc:153269 CYP3A43 ENSDARG00000070021 3 Not determined 1
zgc:86896 ARPC1A ENSDARG00000090369 3 Normal 1

The following reported genes could not be linked automatically to a zebrafish gene:

  • BCL2L11
  • BMF
  • CYP2C9
  • HHEX
  • TRIM4
  • ZKSCAN5
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