GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
ankrd55 ANKRD55 ENSDARG00000053869 5 Not determined 6
cd247l CD247 ENSDARG00000077240 1 Not determined 6
ddx6 DDX6 ENSDARG00000061338 4 Not determined 2
LOC100005846 ELMO1 ENSDARG00000055400 None Not determined 8
LOC558432 SPRED2 ENSDARG00000052435 2 Not determined 3
LOC569515 CDK4 ENSDARG00000030163 2 Not determined 1
NP_998256.1 ELMO1 ENSDARG00000019258 2 Not determined 8
ptpn2a PTPN2 ENSDARG00000016481 4 Not determined 13
ptpn2b PTPN2 ENSDARG00000035986 2 Not determined 13
SH2B3 (1 of 2) SH2B3 ENSDARG00000069958 None Not determined 19
si:dkeyp-1e8.2 SH2B3 ENSDARG00000093095 None Not determined 19
si:dkeyp-72h1.1 LBH ENSDARG00000095347 None Not determined 3
spred2 SPRED2 ENSDARG00000008372 1 Not determined 3
stat4 STAT4 ENSDARG00000028731 3 Not determined 19
traf1 TRAF1 ENSDARG00000069482 1 Not determined 3
ube2l3a UBE2L3 ENSDARG00000019188 None Not determined 8
ube2l3b UBE2L3 ENSDARG00000027141 1 Not determined 8
wu:fk48d07 DDX6 ENSDARG00000018425 3 Not determined 2
zgc:153726 CDK4 ENSDARG00000087937 1 Not determined 1
zgc:66337 LBH ENSDARG00000087377 None Not determined 3

The following reported genes could not be linked automatically to a zebrafish gene:

  • IFI16
  • UBASH3A
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