GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
celsr1a CELSR2 ENSDARG00000069185 8 Not determined 17
CELSR2 CELSR2 ENSDARG00000088231 4 Not determined 17
celsr2l CELSR2 ENSDARG00000019726 2 Not determined 17
KIAA1462 (2 of 2) KIAA1462 ENSDARG00000088405 5 Not determined 2
lipf LIPA ENSDARG00000018529 None Not determined 2
LOC100001168 KIAA1462 ENSDARG00000089871 6 Not determined 2
morf4l1 MORF4L1 ENSDARG00000041155 1 Not determined 1
PDGFD PDGFD ENSDARG00000077677 3 Not determined 3
ppap2b PPAP2B ENSDARG00000059933 None Not determined 4
si:dkey-159a18.1 SORT1 ENSDARG00000056145 1 Not determined 13
si:dkey-30k22.7 CELSR2 ENSDARG00000037286 4 Not determined 17
sort1a SORT1 ENSDARG00000029402 1 Not determined 13
sort1b SORT1 ENSDARG00000056252 10 Not determined 13
zgc:158309 PPAP2B ENSDARG00000069940 7 Not determined 4

The following reported genes could not be linked automatically to a zebrafish gene:

  • ADAMTS7
  • PHACTR1
  • PHACTR1
  • PSRC1
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