GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3).

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
gata3 GATA3 ENSDARG00000016526 4 Not determined 1
rel REL ENSDARG00000055276 4 Not determined 10
si:busm1-160c18.1 HLA-DRA ENSDARG00000053739 2 Not determined 21
si:busm1-194e12.11 HLA-DRA ENSDARG00000055441 1 Not determined 21
si:busm1-228j01.3 HLA-DRA ENSDARG00000086294 2 Not determined 21
si:busm1-228j01.5 HLA-DRA ENSDARG00000079593 3 Not determined 21
si:ch1073-403i13.1 HLA-DRA ENSDARG00000001832 None Not determined 21
si:ch73-211l2.3 HLA-DRA ENSDARG00000075932 1 Not determined 21
si:dkeyp-2h4.2 HLA-DRA ENSDARG00000031745 None Not determined 21
si:zfos-2070c2.1 HLA-DRA ENSDARG00000070206 None Not determined 21
si:zfos-367g9.1 HLA-DRA ENSDARG00000074816 1 Not determined 21
zgc:123107 HLA-DRA ENSDARG00000020286 None Not determined 21

The following reported genes could not be linked automatically to a zebrafish gene:

  • PVT1
  • PVT1
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