GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association study in alopecia areata implicates both innate and adaptive immunity.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
prdx5 PRDX5 ENSDARG00000055064 None Not determined 3
si:busm1-160c18.1 HLA-DQA2 ENSDARG00000053739 2 Not determined 17
si:busm1-194e12.11 HLA-DQA2 ENSDARG00000055441 1 Not determined 17
si:busm1-228j01.3 HLA-DQA2 ENSDARG00000086294 2 Not determined 17
si:busm1-228j01.5 HLA-DQA2 ENSDARG00000079593 3 Not determined 17
si:ch1073-403i13.1 HLA-DQA2 ENSDARG00000001832 None Not determined 17
si:ch211-160b7.1 CTLA4 ENSDARG00000095070 None Not determined 9
si:ch73-211l2.3 HLA-DQA2 ENSDARG00000075932 1 Not determined 17
si:dkey-166n8.9 IKZF4 ENSDARG00000037068 None Not determined 5
si:dkeyp-2h4.2 HLA-DQA2 ENSDARG00000031745 None Not determined 17
si:zfos-2070c2.1 HLA-DQA2 ENSDARG00000070206 None Not determined 17
si:zfos-367g9.1 HLA-DQA2 ENSDARG00000074816 1 Not determined 17
stx17 STX17 ENSDARG00000006869 1 Not determined 1
zgc:123107 HLA-DQA2 ENSDARG00000020286 None Not determined 17

The following reported genes could not be linked automatically to a zebrafish gene:

  • ICOS
  • IL2
  • IL21
  • IL2RA
  • ULBP3
  • ULBP6
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