GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
A5D6S4_DANRE C5 ENSDARG00000021004 8 Not determined 2
ankrd55 ANKRD55 ENSDARG00000053869 5 Not determined 6
ccr6a CCR6 ENSDARG00000087474 4 Not determined 7
ccr6b CCR6 ENSDARG00000038968 2 Not determined 7
cd247l CD247 ENSDARG00000077240 1 Not determined 6
ik:tdsubc_1e8 RBPJ ENSDARG00000003398 None Not determined 1
il6st IL6ST ENSDARG00000030498 5 Normal 3
irf5 IRF5 ENSDARG00000045681 None Not determined 14
LOC558432 SPRED2 ENSDARG00000052435 2 Not determined 3
mhc2dab HLA-DRB1 ENSDARG00000079105 None Not determined 35
NP_001091732.1 HLA-DRB1 ENSDARG00000071168 1 Not determined 35
pou3f3a POU3F1 ENSDARG00000042032 1 Not determined 3
prkcq PRKCQ ENSDARG00000034173 3 Not determined 6
ptpn22 PTPN22 ENSDARG00000075062 5 Not determined 17
pxk PXK ENSDARG00000063195 2 Not determined 2
rbpjb RBPJ ENSDARG00000052091 2 Not determined 1
rel REL ENSDARG00000055276 4 Not determined 10
SH2B3 (1 of 2) SH2B3 ENSDARG00000069958 None Not determined 19
si:busm1-104n07.3 HLA-DRB1 ENSDARG00000074510 1 Normal 35
si:busm1-160c18.3 HLA-DRB1 ENSDARG00000053738 None Not determined 35
si:busm1-160c18.3 HLA-DRB1 ENSDARG00000093706 None Not determined 35
si:busm1-194e12.12 HLA-DRB1 ENSDARG00000055447 None Not determined 35
si:busm1-228j01.4 HLA-DRB1 ENSDARG00000088872 2 Not determined 35
si:busm1-228j01.6 HLA-DRB1 ENSDARG00000041705 1 Not determined 35
si:ch211-153j24.4 BATF ENSDARG00000011818 None Not determined 2
si:ch211-160b7.1 CTLA4 ENSDARG00000095070 None Not determined 9
si:ch211-274c22.6 TNFAIP3 ENSDARG00000027777 5 Not determined 11
si:dkey-19j7.2 AFF3 ENSDARG00000079575 11 Not determined 3
si:dkeyp-1e8.2 SH2B3 ENSDARG00000093095 None Not determined 19
si:zfos-2070c2.3 HLA-DRB1 ENSDARG00000076307 None Not determined 35
spred2 SPRED2 ENSDARG00000008372 1 Not determined 3
stat4 STAT4 ENSDARG00000028731 3 Not determined 19
traf1 TRAF1 ENSDARG00000069482 1 Not determined 3
wu:fd58b11 HLA-DRB1 ENSDARG00000054921 None Not determined 35
zgc:153067 HLA-DRB1 ENSDARG00000056330 2 Not determined 35
zgc:194281 C5orf30 ENSDARG00000093498 None Not determined 1

The following reported genes could not be linked automatically to a zebrafish gene:

  • CCL21
  • CD40
  • IKZF3
  • IL2
  • IL21
  • IL2RA
  • KIF3
  • TNFRSF14
  • UBASH3A
Short-link