GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL).

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
il10 IL10 ENSDARG00000078147 4 Normal 11
IL17REL IL17REL ENSDARG00000089131 2 Not determined 2
nkx2.3 NKX2-3 ENSDARG00000039095 None Not determined 10
nkx2.7 NKX2-3 ENSDARG00000021232 1 1 phenotype 10
otud3 OTUD3 ENSDARG00000022648 None Not determined 4
si:busm1-160c18.1 HLA-DRA ENSDARG00000053739 2 Not determined 21
si:busm1-194e12.11 HLA-DRA ENSDARG00000055441 1 Not determined 21
si:busm1-228j01.3 HLA-DRA ENSDARG00000086294 2 Not determined 21
si:busm1-228j01.5 HLA-DRA ENSDARG00000079593 3 Not determined 21
si:ch1073-403i13.1 HLA-DRA ENSDARG00000001832 None Not determined 21
si:ch73-211l2.3 HLA-DRA ENSDARG00000075932 1 Not determined 21
si:dkeyp-2h4.2 HLA-DRA ENSDARG00000031745 None Not determined 21
si:zfos-2070c2.1 HLA-DRA ENSDARG00000070206 None Not determined 21
si:zfos-367g9.1 HLA-DRA ENSDARG00000074816 1 Not determined 21
wwp1 SMURF1 ENSDARG00000016086 4 Not determined 2
zgc:123107 HLA-DRA ENSDARG00000020286 None Not determined 21
zgc:55877 KPNA7 ENSDARG00000027169 2 Not determined 1
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