GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
BST1 BST1 ENSDARG00000086451 None Not determined 4
LRRK2 LRRK2 ENSDARG00000006169 6 Not determined 8
nucks1b NUCKS1 ENSDARG00000012777 1 Not determined 4
pm20d1.1 PM20D1 ENSDARG00000037551 1 Not determined 1
pm20d1.2 PM20D1 ENSDARG00000062096 None Not determined 1
slc41a1 SLC41A1 ENSDARG00000070214 1 Not determined 3
slc45a3 SLC45A3 ENSDARG00000075975 4 Not determined 3
wu:fc07e02 NUCKS1 ENSDARG00000078473 2 Not determined 4
zgc:77158 SLC45A3 ENSDARG00000013784 2 Not determined 3

The following reported genes could not be linked automatically to a zebrafish gene:

  • PARK16
  • RAB7L1
  • SNCA
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