GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
arhgap1 ARHGAP1 ENSDARG00000024324 1 Not determined 2
cd40 TNFRSF11A ENSDARG00000054968 None Not determined 6
crhr1 CRHR1 ENSDARG00000003989 4 Not determined 3
ctnnb1 CTNNB1 ENSDARG00000014571 1 Not determined 2
CTNNB1 CTNNB1 ENSDARG00000023472 2 Not determined 2
esr1 ESR1 ENSDARG00000004111 1 Not determined 14
foxl1 FOXL1 ENSDARG00000008133 1 Not determined 3
LOC100332699 HDAC5 ENSDARG00000089416 1 Not determined 1
LOC100333821 TNFRSF11A ENSDARG00000087804 None Not determined 6
LOC557486 HDAC5 ENSDARG00000075139 3 Not determined 1
LOC558595 AKAP11 ENSDARG00000075435 4 Normal 2
LOC795858 TNFRSF11A ENSDARG00000095718 None Not determined 6
lrp5 LRP5 ENSDARG00000006921 6 Not determined 3
mef2ca MEF2C ENSDARG00000029764 4 Not determined 8
mef2cb MEF2C ENSDARG00000009418 1 Not determined 8
ngfr TNFRSF11A ENSDARG00000057143 2 Not determined 6
Q502M3_DANRE SPTBN1 ENSDARG00000036402 6 Not determined 5
si:ch211-261n11.7 TNFRSF11A ENSDARG00000068966 None Not determined 6
si:ch211-261n11.8 TNFRSF11A ENSDARG00000089901 None Not determined 6
si:dkey-23c22.5 TNFRSF11A ENSDARG00000092892 1 Not determined 6
si:dkey-23c22.6 TNFRSF11A ENSDARG00000068991 None Not determined 6
si:dkey-23c22.7 TNFRSF11A ENSDARG00000095193 None Not determined 6
si:dkey-23c22.9 TNFRSF11A ENSDARG00000092381 None Not determined 6
sox6 SOX6 ENSDARG00000015536 5 Not determined 5
sp7 SP7 ENSDARG00000019516 2 Not determined 3
SPTBN1 (1 of 2) SPTBN1 ENSDARG00000079113 4 Not determined 5
stard3nl STARD3NL ENSDARG00000045421 None Not determined 4
ZBTB40 ZBTB40 ENSDARG00000091762 6 Not determined 5
zgc:153631 TNFRSF11A ENSDARG00000068993 1 Not determined 6
zgc:153759 TNFRSF11A ENSDARG00000068969 None Not determined 6
zgc:158862 TNFRSF11A ENSDARG00000068963 None Not determined 6

The following reported genes could not be linked automatically to a zebrafish gene:

  • DCDC5
  • FLJ42280
  • FLJ42280
  • GPR177
  • GPR177
  • MEPE
  • MEPE
  • TNFRSF11B
  • TNFRSF11B
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