GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
ifnphi2 IFNK ENSDARG00000069012 None Not determined 5
ifnphi3 IFNK ENSDARG00000070676 1 Not determined 5
si:dkey-110c1.7 UNC13A ENSDARG00000061829 7 Not determined 3
UNC13A (5 of 5) UNC13A ENSDARG00000091647 1 Not determined 3
UNC13A (3 of 5) UNC13A ENSDARG00000090528 None Not determined 3
UNC13A (2 of 5) UNC13A ENSDARG00000091504 None Not determined 3
UNC13A (1 of 5) UNC13A ENSDARG00000087214 1 Not determined 3
zgc:100846 C9orf72 ENSDARG00000011837 1 Not determined 3

The following reported genes could not be linked automatically to a zebrafish gene:

  • MOBKL2B
  • MOBKL2B
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