GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Common body mass index-associated variants confer risk of extreme obesity.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
fbn2a FBN2 ENSDARG00000051896 13 Not determined 3
fto FTO ENSDARG00000044216 3 Not determined 32
itpr3 ITPR3 ENSDARG00000061741 15 Not determined 2
LOC100000903 PRF1 ENSDARG00000030394 3 Not determined 1
LOC569443 PRF1 ENSDARG00000060662 2 Not determined 1
rtn4a RTN4 ENSDARG00000044601 None Not determined 1
si:ch211-103n10.4 PRF1 ENSDARG00000037598 None Not determined 1
si:dkey-89b17.6 PRF1 ENSDARG00000001572 1 Not determined 1
tram1 TRAM1L1 ENSDARG00000019137 1 Not determined 2
zgc:113278 TRAM1L1 ENSDARG00000037813 1 Not determined 2
zgc:163021 PRF1 ENSDARG00000024522 2 Not determined 1

The following reported genes could not be linked automatically to a zebrafish gene:

  • C20orf133
  • FLJ20309
  • MLN
  • MUC15
  • RAFTLIN
  • RARB
  • ZNF248
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