GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
bach2 BACH2 ENSDARG00000004074 2 Not determined 14
ctsh CTSH ENSDARG00000041108 3 Not determined 3
ctskl CTSH ENSDARG00000042753 2 Not determined 3
erbb3a ERBB3 ENSDARG00000006202 1 Not determined 8
erbb3b ERBB3 ENSDARG00000036993 7 Not determined 8
LOC557210 BACH2 ENSDARG00000036569 4 Not determined 14
LOC563218 C16orf75 ENSDARG00000074444 None Not determined 2
prkcq PRKCQ ENSDARG00000034173 3 Not determined 6
ptpn22 PTPN22 ENSDARG00000075062 5 Not determined 17
ptpn2a PTPN2 ENSDARG00000016481 4 Not determined 13
ptpn2b PTPN2 ENSDARG00000035986 2 Not determined 13
si:ch211-160b7.1 CTLA4 ENSDARG00000095070 None Not determined 9
zgc:110239 CTSH ENSDARG00000077664 1 Not determined 3
zgc:56230 CLEC16A ENSDARG00000038094 3 Not determined 13

The following reported genes could not be linked automatically to a zebrafish gene:

  • C12orf30
  • C1QTNF6
  • HLA
  • IL2RA
  • PRM3
  • TNP2
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