GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
adamts13 ADAMTS13 ENSDARG00000076270 2 Not determined 3
alp ALPL ENSDARG00000015546 1 Not determined 6
chuk CHUK ENSDARG00000011662 2 Not determined 1
cpn1 CPN1 ENSDARG00000005185 1 Not determined 4
erlin1 ERLIN1 ENSDARG00000021991 None Not determined 2
ggt1 GGT1 ENSDARG00000023526 None Not determined 4
hnf1a HNF1A ENSDARG00000009470 None Not determined 21
jmjd1c JMJD1C ENSDARG00000079939 5 Not determined 11
LOC100148888 C22orf36 ENSDARG00000091128 1 Not determined 2
LOC569014 GGT1 ENSDARG00000018342 None Not determined 4
LOC571586 JMJD1C ENSDARG00000077805 10 Not determined 11
LOC794105 GGT1 ENSDARG00000087063 None Not determined 4
pou2f1b POU2F1 ENSDARG00000007996 2 Not determined 1
RAP1GAP (3 of 3) RAP1GAP ENSDARG00000053272 1 Not determined 1
RAP1GAP (2 of 3) RAP1GAP ENSDARG00000088735 None Not determined 1
reep3 REEP3 ENSDARG00000004160 1 Not determined 2
reep3l REEP3 ENSDARG00000017569 1 Not determined 2
samm50 SAMM50 ENSDARG00000045814 2 Not determined 4
samm50l SAMM50 ENSDARG00000039681 1 Not determined 4
si:ch211-286e11.2 C22orf36 ENSDARG00000074308 1 Not determined 2
si:dkey-222h21.12 GGT1 ENSDARG00000092350 None Not determined 4
si:dkey-222h21.13 GGT1 ENSDARG00000087054 None Not determined 4
si:dkey-222h21.14 GGT1 ENSDARG00000075055 2 Not determined 4
zgc:162025 C12orf43 ENSDARG00000046141 None Not determined 4
zgc:175180 RAP1GAP ENSDARG00000056554 3 Not determined 1
zgc:92195 PNPLA3 ENSDARG00000044086 1 Not determined 6

The following reported genes could not be linked automatically to a zebrafish gene:

  • ABO
  • C12orf27
  • GPLD1
  • NBPF3
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