GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Newly identified genetic risk variants for celiac disease related to the immune response.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
A5PLF6_DANRE ADAD1 ENSDARG00000089181 3 Not determined 3
LOC799279 IL1RL1 ENSDARG00000090844 None Not determined 8
lpp LPP ENSDARG00000023578 1 Not determined 10
SH2B3 (1 of 2) SH2B3 ENSDARG00000069958 None Not determined 19
si:ch211-152p11.4 RGS1 ENSDARG00000079705 3 Not determined 3
si:ch211-233a24.2 KIAA1109 ENSDARG00000062330 15 Not determined 2
si:ch211-251n20.3 RGS1 ENSDARG00000089077 None Not determined 3
si:dkey-165i4.1 ATXN2 ENSDARG00000052897 5 Normal 10
si:dkeyp-1e8.2 SH2B3 ENSDARG00000093095 None Not determined 19
slc9a2 SLC9A4 ENSDARG00000058780 2 Not determined 2
tagap TAGAP ENSDARG00000043475 4 Not determined 7
zgc:110585 SCHIP1 ENSDARG00000035175 None Not determined 3
zgc:153615 SCHIP1 ENSDARG00000038981 None Not determined 3
zgc:77799 TAGAP ENSDARG00000002353 None Not determined 7

The following reported genes could not be linked automatically to a zebrafish gene:

  • CCR1
  • CCR3
  • IL12A
  • IL18R1
  • IL18RAP
  • IL2
  • IL21
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