(GWAS data used on the Zebrafish Mutation Project Web site comes from

Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
kcnb2 KCNB2 ENSDARG00000038862 1 Not determined 4
LOC100001603 FAM5C ENSDARG00000061051 4 Not determined 2
LOC100330048 FAM5C ENSDARG00000075352 3 Not determined 2
PDE4B (2 of 3) PDE4B ENSDARG00000087449 None Not determined 3
PDE4B (1 of 3) PDE4B ENSDARG00000032868 3 Not determined 3
pde4bb PDE4B ENSDARG00000074233 1 Not determined 3
RYR2 (1 of 3) RYR2 ENSDARG00000056058 1 Not determined 5
ryr2a RYR2 ENSDARG00000079171 1 Not determined 5
ryr2b RYR2 ENSDARG00000003706 1 Not determined 5
si:dkey-192j17.1 KCNB2 ENSDARG00000088842 1 Not determined 4
slit2 SLIT2 ENSDARG00000004246 5 Not determined 1
wrn WRN ENSDARG00000053065 6 Not determined 1
zgc:175108 FAM5C ENSDARG00000076351 5 Not determined 2
zgc:64174 OBFC1 ENSDARG00000007734 3 Not determined 5

The following reported genes could not be linked automatically to a zebrafish gene:

  • NOLA1
  • SPACA1