GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
cdkal1 CDKAL1 ENSDARG00000022122 2 Not determined 23
cdkn2b CDKN2B ENSDARG00000037262 2 Not determined 30
cdkn2b CDKN2A ENSDARG00000037262 2 Not determined 25
fto FTO ENSDARG00000044216 3 Not determined 32
igf2bp2a IGF2BP2 ENSDARG00000003421 1 Not determined 12
igf2bp2b IGF2BP2 ENSDARG00000061661 2 Not determined 12
kcnj11 KCNJ11 ENSDARG00000051880 None Not determined 5
kcnj11l KCNJ11 ENSDARG00000031438 None Not determined 5
LOC100002134 SLC30A8 ENSDARG00000054584 1 Not determined 16
LOC560642 SLC30A8 ENSDARG00000057629 None Not determined 16
pparg PPARG ENSDARG00000031848 5 2 normal 8
tcf7l2 TCF7L2 ENSDARG00000004415 5 Not determined 23

The following reported genes could not be linked automatically to a zebrafish gene:

  • HHEX
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