Search Zebrafish Mutation Project
e.g. ENSDARG00000093395 or slc2a11b or ENSG00000135862 or LAMC1 or sa457
You can look for mutant lines by browsing a complete list or by searching for a particular gene
tlr4al
- Ensembl ID:
- ENSDARG00000075671
- ZFIN ID:
- ZDB-GENE-090507-2
- Description:
- Novel protein similar to toll-like receptor 4 family [Source:UniProtKB/TrEMBL;Acc:B8A690]
- Human Orthologue:
- TLR4
- Human Description:
- toll-like receptor 4 [Source:HGNC Symbol;Acc:11850]
- Mouse Orthologue:
- Tlr4
- Mouse Description:
- toll-like receptor 4 Gene [Source:MGI Symbol;Acc:MGI:96824]
Alleles
There is 1 allele of this gene:
| Allele name | Consequence | Status | Availability Estimate |
|---|---|---|---|
| sa11530 | Nonsense | Available for shipment | Available now |
Mutation Details
- Allele Name:
- sa11530
- Current Status:
-
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs. - Availability:
-
Order Allele From ZIRC
Order Allele From EZRC - Mutation:
- T > A
- Consequence:
- Nonsense
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000113952 | Nonsense | 95 | 793 | 2 | 2 |
- Genomic Location (Zv9):
- Chromosome 13 (position 18570254)
- Other Location(s):
-
Assembly Chromosome Position GRCz10 13 18390289 GRCz11 13 18521281 - KASP Assay ID:
- None (used for ordering genotyping assays from LGC Genomics)
- KASP Sequence:
- ACTGGAAACCCYATTAYATATTWTGCTCCTGGATGCTTGAATACTTTAWA[T/A]AATCTGCAAAGGCTWGTTCTYGTGGATRYTGGTCTTGAATCCTTACAGCY
- Associated Phenotype:
- Not determined
GWAS
This gene's human homologue has been identified in the following GWAS studies:
- Obesity-related traits: Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (View Study)
(GWAS data comes from http://www.genome.gov/gwastudies/.)
Register
If you would like to be informed when the status of this gene changes (for example, a new allele is generated or an allele is made available for distribution) then please enter your details below:
