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e.g. ENSDARG00000093395 or slc2a11b or ENSG00000135862 or LAMC1 or sa457
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tlr8b
- Ensembl ID:
- ENSDARG00000073675
- ZFIN ID:
- ZDB-GENE-040219-12
- Description:
- cDNA, clone cssl:d0554 [Source:UniProtKB/TrEMBL;Acc:A8BBI2]
- Human Orthologue:
- TLR8
- Human Description:
- toll-like receptor 8 [Source:HGNC Symbol;Acc:15632]
- Mouse Orthologue:
- Tlr8
- Mouse Description:
- toll-like receptor 8 Gene [Source:MGI Symbol;Acc:MGI:2176887]
Alleles
There is 1 allele of this gene:
| Allele name | Consequence | Status | Availability Estimate |
|---|---|---|---|
| sa45416 | Nonsense | Mutation detected in F1 DNA | During 2018 |
Mutation Details
- Allele Name:
- sa45416
- Current Status:
-
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs. - Availability:
- We currently estimate that this allele will be available during 2018.
- Mutation:
- T > A
- Consequence:
- Nonsense
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000114208 | Nonsense | 37 | 802 | 1 | 2 |
- Genomic Location (Zv9):
- Chromosome 10 (position 45346568)
- Other Location(s):
-
Assembly Chromosome Position GRCz10 10 43997631 GRCz11 10 43844428 - KASP Assay ID:
- None (used for ordering genotyping assays from LGC Genomics)
- KASP Sequence:
- None
- Flanking Sequence:
- TTGGAGAAAACTCCCCTGCGATGTGAATCTCTCCAACACATCCGTCACCT[T/A]GGACTGCTCAGAAAGATATTTAAAGAAAATCCCCAAAAACCTGATCTGGA
- Associated Phenotype:
- Not determined
GWAS
This gene's human homologue has been identified in the following GWAS studies:
- Celiac disease: Multiple common variants for celiac disease influencing immune gene expression. (View Study)
(GWAS data comes from http://www.genome.gov/gwastudies/.)
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